BIOCHEMISTRY

Course Description

The main topics are water and pH, the structure of carbohydrates, lipids, amino acids, proteins and nucleic acids, enzymes including mechanism of action, enzyme kinetics, regulation of enzyme activity, coenzymes, and bioenergetics. The structure of proteins, carbohydrates and lipids, cell membranes, are covered as well as structures and mechanisms of action of several membrane channels, pumps and receptors. Transducing and storing energy is covered as part of the introduction to metabolism. The molecular details of nucleic acid structure, DNA replication, RNA synthesis, processing and regulation, gene expression, protein synthesis, techniques in protein biochemistry will also be covered. Transcription of DNA into RNA and the translation at the ribosome are among the emphasized areas as well as protein/enzyme structure/function, macromolecule structures.

BIOCHEMISTRY

Evaluation Tools (Active Term)

Course outcomes

No course outcomes have been defined yet.

Course Syllabus

Reference Books & Course Materials

1. 01 FUNDAMENTALS OF BIOCHEMISTRY by VOET, VOET, PRATT, Upgrade Edition, ISBN:0-471-41759-9
2. 02 Harper's Illustrated Biochemistry by Murray et al., McGraw Hill, 29th Ed.
3. 03 Lehninger - Principles of Biochemistry, 8th ed.

Learning Outcomes

1. L01 Explain the properties of water, ionization, Keq, pH and pKa in relation to water and other biomolecules and compute formulas in relation to pH, pKa and acid/base concentrations SOLO 3.5
2. L02 Distinguish and characterize the different classes of amino acids, their unique features and isoelectric points, and identify and explain different levels of protein structures SOLO 3.5
3. L03 Outline the process of protein folding and degradation and explain and characterize protein metabolism, amino acid deamination, and protein metabolism disorders SOLO 3.6
4. L04 Outline and describe the steps of protein purification SOLO 3
5. L05 Identify and describe the different categories and functions of carbohydrates SOLO 2.5
6. L06 Identify and describe the different categories and functions of lipids SOLO 2.5
7. L07 Explain DNA and RNA structures, nucleotides and outline research that led to the discovery of DNA and inheritance, including DNA mutations and DNA repair SOLO 3.5
8. L08 Outline the stages and characteristics of DNA replication, transcription and translation and the roles of enzymes involved, including post transcriptional and post translational modifications SOLO 3
9. L09 Describe the functions of enzymes and their characteristics and compute enzymatic parameters such as Km, Vmax, 1/2Vmax and use the Michaelis-Menten equation with and without inhibitors SOLO 3

Program Outcomes

1. P01 Becoming aware of sufficient theoretical knowledge in basic engineering and agricultural science
2. P02 Having sufficient theoretical knowledge in basic agricultural production especially in pomology, viticulture, olericulture, floriculture and agronomy, and their breeding
3. P03 Being well equiped with practical experiences in agriculture
4. P04 Finding the source of environmental, biotic, abiotic, technical and economical problems in agricultural crops which reduce yield and quality, and create solutions to related problems
5. P05 Defining, classifying and naming cultivated crop plants and knowing how to manage them
6. P06 Breeding of horticultural and field crops, developing new cultivars and producing propagation materials of new developed varieties
7. P07 Applying up-to-date methods and techniques for preserving genetic resources and environment for sustainable use in agricultural commodities
8. P08 Evaluating, asseying and analyzing the changes in cultivation of horticultural and agronomic crops in respect to irrigation, fertilization, defining pests and diseases and after postharvest handling
9. P09 Establishing and managing orchards, vineyards and field crop productions and greenhouse operations
10. P10 Obtaining data in horticulture and field crops along with researching, considering, recording, consulting and expert abilities, project writing and applying
11. P11 Identifying different roles in enchancing individual abilities and skills beside taking responsibilities, participations in team works under any given conditions
12. P12 Easily accessing to appropriate information and thinking analytically in their interested area and subjects. They can do accurate timing and planning in agricultural productions in year round. They think analytically, prepare questionaries, have an exploratory and creative vision and use the obtained knowledge for the benefit of farmers and societies
13. P13 Having ability to transfer information and also able to easily communicate with the people in the field at different levels. They have self - confidence and self- improvement skills as well

Po-Lo Matrix