GENETICS

Course Description

The course covers the genetic properties of prokaryotic and eukaryotic cells in living systems. The main topics of the course are nucleic acids (DNA & RNA) and how they replicate, details of how they transcribe DNA to generate messenger RNA (mRNA), and the process of translation of mRNA to proteins. Expanding on these processes, there is a focus on gene editing techniques, DNA fragmentation and the use of restriction enzymes in molecular cloning techniques. Other topics of discussion include the different types of mutations, DNA repair, DNA recombination, post-transcriptional and post-translational regulation, and small non-coding RNAs. Mitochondrial DNA and mitochondrial diseases are also discussed.

GENETICS

Evaluation Tools (Active Term)

No evaluation items have been defined.

Course outcomes

No course outcomes have been defined yet.

Course Syllabus

Reference Books & Course Materials

1. 01 "Genetics: From Genes to Genomes" (7th Edition) by Leland Hartwell, Michael Goldberg, and Janice Fischer.
2. 02 "The Foundations of Population Genetics" by Daniel Weinreich.

Learning Outcomes

1. L01 Outline and distinguish the similarities and differences in the structure and function of DNA, RNA and proteins. SOLO 3.5
2. L02 Describe the use of genetic tools in DNA analysis technologies. SOLO 3
3. L03 Compare and contrast the differences between prokaryotic and eukaryotic transcription and gene regulation. SOLO 4
4. L04 Discuss the molecular mechanism of protein translation. SOLO 5

Program Outcomes

1. P01 PO1: To identify and use theoretical and applied knowledge as well as up-to-date/cutting edge laboratory techniques and analyses methods in the field of molecular biology and genetics.
2. P02 PO2: To identify problems related to molecular biology and genetics.
3. P03 PO3: To design and conduct experiments through hypothesis driven scientific research; and to analyze and interpret data to find solutions to molecular biology and genetics related problems.
4. P04 PO4: To work independently and as part of research group in a multidisciplinary team setting
5. P05 PO5: To apply the principles of scientific research ethics and academic integrity
6. P06 PO6: To interpret, explain and present primary scientific literature and novel findings in oral, written and visual presentation formats
7. P07 PO7: To evaluate experimental data and theoretical findings by using critical and analytical thinking techniques.
8. P08 PO8: To use the currently acceptable process of preparing research proposals and manuscripts for publishing in scientific journals.
9. P09 PO9: To apply the principles of molecular biology and genetics in generating/finding solutions to social problems / issues.
10. P10 PO10: To identify and implement environmental and laboratory safety procedures.
11. P11 PO11: To identify and apply the necessary professional skill set in projects and jobs involving independent and competitive careers in academia, industrial, medical or clinical research, science education, scientific writing and communication, health care, health care policy and civil service.

Po-Lo Matrix