MEDICAL BIOLOGY AND GENETICS-II

Course Description

The aim of this course is to improve the understanding of medical biology and medical genetics that will form the basis of clinical studies for the students who have taken Medical Biology and Genetics 1 course. At the end of this course, students are expected to understand the changes in genetic material and establish the relationship between abberations and diseases. In addition, have knowledge about how these mutations are detected. For this purpose, classification of mutations, harmful mutations in humans, mutations occurring due to replication errors, spontaneous mutations and induced mutations, chromosome mutations, changes in chromosome number and order, chromosomal diseases, DNA organization in chromosomes- Techniques, cancer, recombinant DNA technology, applications of genomics and proteomic biotechnology, gene therapy, and genome editing are described.

MEDICAL BIOLOGY AND GENETICS-II

Evaluation Tools (Active Term)

No evaluation items have been defined.

Course outcomes

No course outcomes have been defined yet.

Course Syllabus

Reference Books & Course Materials

1. 01 Molecular Biology of the Cell 6th Ed. Bruce & Alberts
2. 02 Emery’s Elements of Medical Genetics 15th Ed. Turnpenny PD, Ellard S,
3. 03 Genetics in Medicine 7th Ed. Thomson & Thomson
4. 04 Current scientific literature

Learning Outcomes

1. L01 Define and explain the different classifications of genetic mutations SOLO 3
2. L02 Summarize brief understanding on the harmful effects of mutations in humans SOLO 4
3. L03 Define and explain the structural and numerical mutations of the chromosomes and their related diseases SOLO 3
4. L04 Summarize brief understanding of genomic organization in eukaryotic cells SOLO 4
5. L05 Define and explain the Recombinant DNA Technology and Gene Editing SOLO 3
6. L06 Demonstrate brief understanding on the basics of Genomics and Proteomics SOLO 4
7. L07 Summarize brief understanding of the hallmarks of the Cancer Biology SOLO 4
8. L08 Define and explain the details of Molecular Diagnostic Techniques SOLO 3
9. L09 Summarize brief understanding of Medical Genetics SOLO 4

Program Outcomes

1. P01 The students graduating from the program of dentistry will be able to describe the human body systems and functions and relations to the dentofacial system, recognize pathological conditions, list the preventive measures and express clearly their necessity and importance and act as competent, creative, and ethical practitioners who communicate effectively and view the human organism as an integrated whole.
2. P02 The students graduating from the program of dentistry will be able to specialize in the main branches of dentistry, apply ethical and legal standards in research, design and implement scientific projects, and engage in lifelong professional development to contribute to contemporary dentistry.
3. P03 The students graduating from the program of dentistry will be able to explain the etiology and pathogenesis of oral and dental diseases, perform accurate and differential diagnoses, and apply preventive and therapeutic approaches in accordance with national and international standards.
4. P04 The students graduating from the program of dentistry will be able to effectively use science and technology in dental practice, operate dental equipment and materials safely, apply aseptic and antiseptic principles, and manage anesthesia procedures and possible complications.
5. P05 The students graduating from the program of dentistry will be able to follow current scientific literature, principles of evidence-based dentistry, critically interpret new information, continuously update their theoretical and practical knowledge, and apply evidence-based knowledge to clinical practice, maintain a lifelong commitment to professional growth and learning while embracing lifelong learning.
6. P06 The students graduating from the program of dentistry will be able to efficiently use dental technical instruments and materials for accurate diagnosis and treatment, identify rules of operation and management while maintaining high standards of hygiene and safety.
7. P07 The students graduating from the program of dentistry will be able to critically evaluate and integrate knowledge from various health disciplines, analyze patient data, and perform comprehensive differential diagnoses through interdisciplinary collaboration.
8. P08 The students graduating from the program of dentistry will be able to design and implement scientific research projects, collect and manage patient data accurately, analyze findings objectively, and contribute to scientific advancement in dentistry.
9. P09 The students graduating from the program of dentistry will be able to demonstrate responsibility and problem-solving skills by diagnosing, differentiating, and developing appropriate treatment plans for various oral, periodontal, and maxillofacial conditions.
10. P10 The students graduating from the program of dentistry will be able to communicate effectively and empathetically with patients, offer and implement the best treatment options, and adhere to legal and ethical responsibilities during dental practice.
11. P11 The students graduating from the program of dentistry will be able to promote preventive oral health care, uphold ethical and social responsibility, and contribute to community well-being through leadership, education, and public engagement.

Po-Lo Matrix