MEDICAL BIOLOGY AND GENETICS-I

Course Description

The aim of this course is to improve the understanding medical biology and medical genetics. In this context, the structure of eukaryotic cell, identification of cell compartments and organelles, cell cycle, details of the cell division, mitosis and meiosis, are described. By introducing inheritance models, information is given about Mendelian Genetics and the extensions of Mendelian genetics. Drawing and analysis of the Pedigree is described. The structure and analysis of DNA, DNA replication, the organization of the DNA in chromosomes, that is, the content of the information encoded are explained. Genetic code and Transcription of DNA to RNA is explained. In addition, translation of mRNA into proteins described. DNA Mutations and DNA damage repair are described and regulation of gene expression is explained.

MEDICAL BIOLOGY AND GENETICS-I

Evaluation Tools (Active Term)

Course outcomes

No course outcomes have been defined yet.

Course Syllabus

Reference Books & Course Materials

1. 01 Molecular Biology of the Cell 6th Ed. Bruce & Alberts
2. 02 Emery’s Elements of Medical Genetics 15th Ed. Turnpenny PD, Ellard S,
3. 03 Genetics in Medicine 7th Ed. Thomson & Thomson
4. 04 Current scientific literature

Learning Outcomes

1. L01 Define key genetic concepts and compare prokaryotic and eukaryotic genome organization SOLO 3
2. L02 Classify the stages of the cell cycle and contrast mitosis and meiosis in terms of function and outcomes SOLO 3.5
3. L03 Apply Mendel’s laws to solve genetic cross problems and analyze inheritance patterns in pedigrees SOLO 3.5
4. L04 Differentiate complex inheritance patterns and illustrate environmental effects on gene expression SOLO 3.5
5. L05 Examine non-Mendelian inheritance, including mitochondrial DNA, genomic imprinting, and X-inactivation SOLO 3
6. L06 Explain DNA structure and analyze replication mechanisms, including enzymes, fidelity, and telomere maintenance SOLO 4
7. L07 Describe transcription in prokaryotes and eukaryotes, and evaluate gene regulation and RNA processing SOLO 4
8. L08 Summarize translation steps and assess how the genetic code, ribosomes, and modifications affect protein synthesis SOLO 4.5

Program Outcomes

1. P01 The students graduating from the program of dentistry will be able to describe the human body systems and functions and relations to the dentofacial system, recognize pathological conditions, list the preventive measures and express clearly their necessity and importance and act as competent, creative, and ethical practitioners who communicate effectively and view the human organism as an integrated whole.
2. P02 The students graduating from the program of dentistry will be able to specialize in the main branches of dentistry, apply ethical and legal standards in research, design and implement scientific projects, and engage in lifelong professional development to contribute to contemporary dentistry.
3. P03 The students graduating from the program of dentistry will be able to explain the etiology and pathogenesis of oral and dental diseases, perform accurate and differential diagnoses, and apply preventive and therapeutic approaches in accordance with national and international standards.
4. P04 The students graduating from the program of dentistry will be able to effectively use science and technology in dental practice, operate dental equipment and materials safely, apply aseptic and antiseptic principles, and manage anesthesia procedures and possible complications.
5. P05 The students graduating from the program of dentistry will be able to follow current scientific literature, principles of evidence-based dentistry, critically interpret new information, continuously update their theoretical and practical knowledge, and apply evidence-based knowledge to clinical practice, maintain a lifelong commitment to professional growth and learning while embracing lifelong learning.
6. P06 The students graduating from the program of dentistry will be able to efficiently use dental technical instruments and materials for accurate diagnosis and treatment, identify rules of operation and management while maintaining high standards of hygiene and safety.
7. P07 The students graduating from the program of dentistry will be able to critically evaluate and integrate knowledge from various health disciplines, analyze patient data, and perform comprehensive differential diagnoses through interdisciplinary collaboration.
8. P08 The students graduating from the program of dentistry will be able to design and implement scientific research projects, collect and manage patient data accurately, analyze findings objectively, and contribute to scientific advancement in dentistry.
9. P09 The students graduating from the program of dentistry will be able to demonstrate responsibility and problem-solving skills by diagnosing, differentiating, and developing appropriate treatment plans for various oral, periodontal, and maxillofacial conditions.
10. P10 The students graduating from the program of dentistry will be able to communicate effectively and empathetically with patients, offer and implement the best treatment options, and adhere to legal and ethical responsibilities during dental practice.
11. P11 The students graduating from the program of dentistry will be able to promote preventive oral health care, uphold ethical and social responsibility, and contribute to community well-being through leadership, education, and public engagement.

Po-Lo Matrix