BIOINFORMATICS
- Course
- BIOE305 - BIOINFORMATICS
- Department
- Bioengineering - English - Undergraduate
- Course Type
- Course
- Status
- Required
- Language
- English
- Credit
- 3
- ECTS
- 5
- T+P+L
- 3 + 0 + 0
- Course Coordinator(s)
- Asst. Prof. Dr. Nurten AŞİNA AMCA
- Prerequisite
Course Description
This course will introduce students to bioinformatics concepts, principles, and techniques. They will learn how to access the data archives of genomes and proteins, the tools that have been developed to work with these archives, and the kinds of questions that these data and tools can answer will be covered. During this course human genome project, role of bioinformatics in medicine, spatial and temporal aspects of life, central and peripheral dogma, data archives, the world wide web, electronic publications, computer and computer science, programming, biological classification and nomenclature, tools to evaluate phylogenetic relationships, protein structure, protein structure prediction and determination, clinical implications and 3D protein structure visualisation tools will be covered.
BIOINFORMATICS
Evaluation Tools (Active Term)
| Item | Type | Weight (%) |
|---|---|---|
| Midterm | Midterm | 35 |
| Final | Final | 45 |
| Assignment | Assignment | 20 |
| Total | 100 | |
Course outcomes
- 01 Identify the biological classification and nomenclature.
- 02 Describe protein structure .
- 03 Explain the observables and data archives
- 04 Explain database requirements
- 05 List the clinical implications.
- 06 Explain how cells read the genome from DNA to protein.
- 07 Summarize World Wide Web
- 08 Summarize use of sequences to determine phylogenetic relationships .
- 09 Elaborate on computers and computer science
- 10 Elaborate on importance of bioinformatics.
Course Syllabus
| Week | Topic |
|---|---|
| Week 1 | Introduction to course organisation. |
| Week 2 | Observables and data archives |
| Week 3 | Observables and data archives |
| Week 4 | The World Wide Web |
| Week 5 | The World Wide Web |
| Week 6 | Computers and computer science |
| Week 7 | Review |
| Week 8 | MID-TERM EXAMINATIONS |
| Week 9 | Computers and computer science |
| Week 10 | Biological classification and nomenclature. Use of sequences to determine phylogenetic relationships |
| Week 11 | Use of sequences to determine phylogenetic relationships |
| Week 12 | Introduction to protein structure |
| Week 13 | Protein structure prediction and engineering, Clinical implications, Genomics and proteomics |
| Week 14 | Review |
| Week 15 | Final Exams. |
Reference Books & Course Materials
- 01 Arthur Lesk. Introduction to Bioinformatics. Oxford University Publications, 2014.
Learning Outcomes
- L01 Define and describe bioinformatics. SOLO 2.5
- L02 List the databases and tools used in bioinformatics. SOLO 3
- L03 Solve and interpret practically how to apply the knowledge to the field of study. SOLO 3.33
- L04 Solve and interpret practically how to apply the knowledge to the field of study. SOLO 5
Program Outcomes
- P01 Should have sufficient knowledge in mathematics, science, and subjects specific to the relevant engineering discipline.
- P02 Should have the ability to use theoretical and applied knowledge in mathematics, science, and related engineering disciplines in complex engineering problems.
- P03 Should have the ability to detect, define, formulate, and solve complex engineering problems.
- P04 Should have the ability to select and apply appropriate analysis and modeling methods to solve complex engineering problems.
- P05 Should have the ability to design a complex system, process, device, or product to meet specific requirements under realistic constraints and conditions.
- P06 Should have the ability to apply modern design methods.
- P07 Should have the ability to develop, select, and use modern techniques and tools necessary for the analysis and solution of complex problems encountered in engineering applications.
- P08 Should have the ability to use information technologies effectively.
- P09 Should have the ability to design experiments, for the study of complex problems or discipline-specific research topics.
- P10 Should have the ability to conduct experiments, collect data, analyze and interpret results for the study of complex problems or discipline-specific research topics.
- P11 Should have the ability to work in intradisciplinary teams.
- P12 Should have the ability to work in interdisciplinary teams.
- P13 Should have the skills to work individually.
- P14 Should have the ability to communicate effectively verbally and in writing.
- P15 Should have the knowledge of at least one foreign language.
- P16 Should be able to write effective reports, understand written reports, and prepare design and production reports.
- P17 Should have the ability to make effective presentations.
- P18 Should have the ability to give and have clear and understandable instructions.
- P19 Should gain consciousness (awareness) about the necessity of lifelong learning.
- P20 Should have the ability to access information.
- P21 Should have the ability to follow developments in science and technology and constantly renew himself/herself.
- P22 Should gain the awareness of professional and ethical responsibility and should act in accordance with ethical principles.
- P23 Should gain knowledge about the standards used in engineering applications.
- P24 Should gain knowledge about project management, risk management, and change management practices in business life.
- P25 Should gain awareness about entrepreneurship, and innovation.
- P26 Should gain knowledge about development in sustainability.
- P27 Should gain knowledge about the effects of engineering practices on health, environment, and security at universal and social dimensions and the problems of the age reflected in the field of engineering.
- P28 Awareness should be gained about the legal consequences of engineering solutions.
Po-Lo Matrix
| LO | P01 | P02 | P03 | P04 | P05 | P06 | P07 | P08 | P09 | P10 | P11 | P12 | P13 | P14 | P15 | P16 | P17 | P18 | P19 | P20 | P21 | P22 | P23 | P24 | P25 | P26 | P27 | P28 | Average |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L01 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| L02 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| L03 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| L04 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |