NEUROBIOLOGY
- Course
- AIEN304 - NEUROBIOLOGY
- Department
- Artificial Intelligence Engineering - English - Undergraduate
- Course Type
- Course
- Status
- Required
- Language
- English
- Credit
- 3
- ECTS
- 0
- T+P+L
- 3 + 0 + 0
- Course Coordinator(s)
- -
- Prerequisite
- -
- Keywords
Course Description
The main objective of the course is to introduce main concepts of neurobiology. This course will emphasize basic neural circuits, initiation and propagation of nerve signals, architecture and organization of basic central and peripheral nervous systems, saltatory and passive conduction of nerve signals. Upon completing the course, the students will learn about frequency and amplitude coding of nerve signals, Nernst and Goldman equations, time and space in signal propagation, resting membrane potential of neurons, ionic conductance, the Hodgkin and Huxley model of the action potential, transient inward current and delayed outward current. Topics of the course will also include, derivation of cable model, summation of signals, cellular ionic mechanisms including ion channels and transporters and post-synaptic potential.
NEUROBIOLOGY
Evaluation Tools (Active Term)
No evaluation items have been defined.
Course outcomes
- 01 Identify
- 02 Explain basic central and peripheral nervous system organization, and simple neural circuits
- 03 List electrophysiological recording techniques
- 04 Summarize time & Space in Propagating Signals
- 05 Describe action potentials with both saltatory and passive conduction
- 06 Explain Nernst and Goldman Equation
- 07 Explain Resting Potential of Neuron Membranes
- 08 Summarize Electrical Signals in Cells
- 09 Elaborate on Ionic Conductances
- 10 Elaborate on the Hodgkin-Huxley model of the action potential
Course Syllabus
| Week | Topic |
|---|---|
| Week 1 | Introduction to course organisation. |
| Week 2 | Basic organization of CNS&PNS. |
| Week 3 | Simple Neural Circuits (VOR, stretch) |
| Week 4 | Electrical Signals in Cells |
| Week 5 | Resting Potential of Neuron Membranes |
| Week 6 | Nernst Equation |
| Week 7 | Nernst Equation |
| Week 8 | MID-TERM EXAMINATIONS |
| Week 9 | TIC and DOC; Time & Space in Propagating Signals; Ion Channels |
| Week 10 | Post-synaptic Receptors; Neurotransmitters and Pathology |
| Week 11 | Electrical Variables in Cells; Core Conductor Model; Observations from Action Potentials |
| Week 12 | Derivation of the Cable Model; Time-dependent Solutions |
| Week 13 | Alan Hodgkin and Andrew Huxley; Ionic Conductances; Derivation of the Hodgkin-Huxley Equation; Insights from Hodgkin-Huxley |
| Week 14 | Revision |
| Week 15 | Final Exam |
Reference Books & Course Materials
- 01 Neuroscience (Looseleaf) Fifth Edition 5th Edition Dale Purves, George J. Augustine, David Fitzpatrick, William C. Hall, Anthony-Samuel LaMantia, Leonard E. White
Learning Outcomes
No learning outcomes have been defined.
Program Outcomes
- Adequate knowledge in mathematics, science and engineering subjects pertaining to the relevant discipline; ability to use theoretical and applied knowledge in these areas in complex engineering problems.
- Ability to identify, formulate, and solve complex engineering problems; ability to select and apply proper analysis and modelling methods for this purpose.
- Ability to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the desired result; ability to apply modern design methods for this purpose.
- Ability to devise, select, and use modern techniques and tools needed for analysing and solving complex problems encountered in engineering practice; ability to employ information technologies effectively.
- Ability to design and conduct experiments, gather data, analyse and interpret results for investigating complex engineering problems or discipline specific research questions.
- Ability to work efficiently in intra-disciplinary and multi-disciplinary teams; ability to work individually.
- Ability to communicate effectively in Turkish, both orally and in writing; knowledge of a minimum of one foreign language; ability to write effective reports and comprehend written reports, prepare design and production reports, make effective presentations, and give and receive clear and intelligible instructions.
- Recognition of the need for lifelong learning ; ability to access information, to follow developments in science and technology, and to continue to educate him/herself.
- Consciousness to behave according to ethical principles and professional and ethical responsibility; knowledge on standards used in engineering practice.
- Knowledge about business life practices such as project management, risk management, and change management; awareness in entrepreneurship, innovation; knowledge about sustainable development.
- Knowledge about the global and social effects of engineering practices on health, environment, and safety, and contemporary issues of the century reflected into the field of engineering; awareness of the legal consequences of engineering solutions.
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