PHARMACOGENETICS AND PHARMACOGENOMICS

Course Description

Pharmacogenetics and Pharmacogenomics lecture will be dealing with interaction of genetics and polymorphism on drug pharmacokinetic and pharmacodynamics parameters. The aim of this course is to deal with the basis of gene therapy, genetic variation in the effects of drugs and xenobiotic substances on the body, and in the body’s reactions to drugs, translational, and pharmaceutical research, and application of genomic technologies to new drug discovery. Genetically engineering drugs and their application in treatment of certain diseases such as cancer, diabetes, heart problems, Alzheimer’s and other neurodegenerative diseases and atherosclerosis will be also considered. While genetic variation is an important parameter on drug interactions, the contributions of epigenetic and non-genetic factors to drug disposition and drug response will be explained in this lecture.

PHARMACOGENETICS AND PHARMACOGENOMICS

Evaluation Tools (Active Term)

No evaluation items have been defined.

Course outcomes

No course outcomes have been defined yet.

Course Syllabus

Reference Books & Course Materials

1. 01 Pharmacogenetics: The right drug for you
2. 02 Insights in Pharmacogenetics and Pharmacogenomics: 2021
3. 03 Principles of Pharmacogenetics and Pharmacogenomics

Learning Outcomes

1. L01 Implement the basic principles of molecular biology and genetics SOLO 4
2. L02 Implement genetic variability in genes encoding drug metabolizing enzymes SOLO 4
3. L03 Implement pharmacogenomic applications to a particular drug therapy and alternative approaches SOLO 4

Program Outcomes

1. P01 Gain the ability to apply the Pharmacy profession.
2. P02 Interpret the accuracy and reliability of the current theoretical and practical knowledge in the field of pharmacy, as well as being able to follow and evaluate innovations.
3. P03 Practically apply the knowledge they gain on pharmaceutical sciences. The acquired knowledge and skills allow the graduates to act as the closest health consultant to the public with the ability to inform the public.
4. P04 Evaluate and apply current technology related to basic subjects and principles covering pharmacy and health sciences and take part in in-service training seminars.
5. P05 Know the risks and evaluation of the use of drugs and other chemicals and safe laboratory practices (GMP).
6. P06 Acquire the ability to interpret the findings obtained by qualitative and quantitative measurements and to reach valid scientific results from the data.
7. P07 Prepare pharmaceuticals and provide guidance on the use of pharmaceutical products.
8. P08 Design research and develop projects related to pharmaceutical products; manage and share the results.
9. P09 Be competent to accurately and intelligibly communicate and transfer knowledge about prescription content and pharmaceutical products to the patient / user. The graduates are trained on taking necessary precautions for safe drug usage and encouraging rational drug use, as well as providing consultancy and supervision.
10. P10 Work in an interdisciplinary environment. Graduates can cooperate with other professional groups, participate in vocational training and activities, have proper knowledge and communication skills.
11. P11 Take part in social responsibility projects related to health. Graduates have awareness on sustainable environment and participate in activities and practices related to their profession.
12. P12 Open a community pharmacy, also work in hospital pharmacies, can work in different fields related with pharmaceuticals, cosmetics, medical and herbal products, as well as production and quality control in the pharmaceutical industry. Takes part in the professional development of herself/himself, her/his colleagues and pharmacy students.
13. P13 Implements the legal and professional law and ethics as a health professional, in issues concerning public health.
14. P14 Knows and applies the processes related to drug design from natural or synthetic sources, as well as development, preparation, analysis and metabolism of drugs in the human body.

Po-Lo Matrix