PHARMACOGNOSY-I
- Course
- PHAR301 - PHARMACOGNOSY-I
- Department
- Pharmacy - English - Undergraduate
- Course Type
- Course
- Status
- Required
- Language
- English
- Credit
- 4
- ECTS
- 5
- T+P+L
- 3 + 0 + 3
- Course Coordinator(s)
- Assoc. Prof. Dr. Emmanuel Mshelia HALILU
- Prerequisite
- -
Course Description
Pharmacognosy provides information about pharmacopoeial and related drugs of biological origin. Pharmacognosy I introduces students to botanical and chemical properties and therapeutical uses of plant originated crude drugs which contain carbohydrates (homogeneous, heterogeneous and algal polysaccharides), simple phenolics, tannins, flavonoids, antraquinones, coumarins, glucosinolates and cyanogenetic glycosides as their active constituents. Pharmacognosy I Lab comprises the examination of microscopical characters of powdered crude drugs containing tannins (nut gall), flavonoids(liquorice, ginkgo), cyanogenic glycosides and antraquinones(senna, cascara) as their active constituents and chemical identification (Borntraeger, Cyanidin) and TLC (antraquinones) of the drugs which yield same group of active constituents. General information about the production and quality control of crude drugs are also included.
PHARMACOGNOSY-I
Evaluation Tools (Active Term)
No evaluation items have been defined.
Course outcomes
- 01 1. Describe scope of pharmacognosy
- 02 2. Summarize production and preparation of vegetable drugs
- 03 3. Characterize botanical characters of carbohydrate and glycoside containing vegetable drugs
- 04 4. Analyze chemistry of carbohydrates and glycosides found in vegetable drugs
- 05 5. Apply methods for the isolation of carbohydrates and glycosides from vegetable drugs
- 06 6. Evaluate the therapeutic uses of carbohydrate and glycoside containing drugs
Course Syllabus
| Week | Topic |
|---|---|
| Week 1 | Scope and Practice of pharmacognosy Lab: General information about Pharmacognosy Labs ,Lab demostrationtest |
| Week 2 | Principles related to the commercial production, quality control and Standardization of Natural Products Lab: Moisture and ash determination in Natural Products |
| Week 3 | Carbohydrates; Monosaccharides and oligosaccharides and their derivatives Lab: Production of strach and microscopic examination of starches |
| Week 4 | Carbohydrates; Algal polisaccharides and their drugs. Lab: Microscopic and chemical examination of Agar |
| Week 5 | Carbohydrates; Homogeneous polisaccharides. Lab: Microscopical characteristics of powdered root, bark and leaves |
| Week 6 | Carbohydrates; Heterogeneous polisaccharides; mucilages and gums. Lab: Microscopic examination of mucilage containin drugs and determinaton of swelling index |
| Week 7 | Midterm Exam |
| Week 8 | General information about glycosides, simple phenols and phenolic glycosides Lab: Microscopic and chemical examination of simple phenol glycosides containing drugs |
| Week 9 | Tannins and tannin containing drugs: Lab: Microscopic and chemical examination of tannin containing drugs |
| Week 10 | Flavonoids; Generalities, distribution, chemical structures and uses in therapy. Lab: Microscopic examination of flavonoid containing drugs and chemical identification of flavonoids |
| Week 11 | Flavonoid drugs. Lab: Microscopic examination of flavonoid containing drug and identification of flavonoids in phytomedicines |
| Week 12 | Antraquinones: Generalities, distribution, chemical structures, and uses in therapy. Lab: Microscopic examination of antraquinone containing drugs (roots and rhizomes) and chemical identification of antraquinones |
| Week 13 | Antrquinone containing drugs. Lab Microscopic examination of antraquinone containing drugs (Leaves) and examination of antraquinones in tablets by thin layer chromatography |
| Week 14 | Coumarins, Lignans and cyanogenic glycosides. Lab: Chemical identification of cyanogenic glycosides |
| Week 15 | Glucosinolates Lab: Quiz |
Reference Books & Course Materials
- 01 Trease and Evans Pharmacognosy (2009) William C. Evans, 16th ed. Saunders Elsevier, Edinburgh, London, New York , Philadelphia
- 02 Fundamentals of Pharmacognosy and Phytotherapy(2013) Micheal Heinrich, Joanne Barnes, Simon Gibbons and Elizabeth Williamson, Churchill Livingstone, Elsevier
- 03 Powdered Vegatable Drugs (1968) Betty Jacksoni Derek W. Snowden J. & A. Churchill Ltd. London
- 04 Microscopic characterization of Botanical Medicines (2011) R. Upton, Alison Graff, G. Jolliffe, R. Langer, E. Williamson, D. Swisher, CRC Press, Taylor and Francis Group
Learning Outcomes
- L01 Relate the scope of pharmacognosy and its importance in Pharmacy SOLO 4
- L02 Develop and produce natural products, carry out quality control of natural product which are used for the preparation of drugs SOLO 5
- L03 Explaın the classification and chemical structure of carbohydrates which are found in vegetable drugs and recognize the drugs which contain these carbohydrates SOLO 3
- L04 Recognize the term glycosides and have knovlede about the biosynthesis of glycosides in the plants SOLO 3
- L05 Explaın the simple phenolics, phenolic glycosides, tannins and recognize the vegetable drugs which contain these compounds SOLO 3
- L06 Recognıze the chemical structure and uses of flavonoids and antraquinones in therapy and recognize the vegetable drugs which contain rhese compounds SOLO 2
- L07 Outlıne the general methods which are used for the quality control of vegetable drugs. SOLO 3
- L08 Recognize microscopical characteristics of powdered crude drugs which contain tannins, antraquinones, flavonoids and cyanogenic glycosides SOLO 3
- L09 Conduct the chemical tests and thin layer chromatography in pharmacognosy labs which are used for the identification of tannins, flavonoids, antraquinones and cyanogenic glycosides containing vegetable drugs SOLO 3
- L10 1. Describe scope of pharmacognosy SOLO 3
- L11 2. Summarize production and preparation of vegetable drugs SOLO 4
- L12 3. Characterize botanical characters of carbohydrate and glycoside containing vegetable drugs SOLO 3
- L13 4. Analyze chemistry of carbohydrate and glycosides found in vegetable drugs SOLO 4
- L14 5. Apply methods for the isolation of carbohydrates and glycosides from vegetable drugs SOLO 3
- L15 6. Evaluate the therapeutic uses of carbohydrate and glycoside containing drugs SOLO 5
Program Outcomes
- P01 Gain the ability to apply the Pharmacy profession.
- P02 Interpret the accuracy and reliability of the current theoretical and practical knowledge in the field of pharmacy, as well as being able to follow and evaluate innovations.
- P03 Practically apply the knowledge they gain on pharmaceutical sciences. The acquired knowledge and skills allow the graduates to act as the closest health consultant to the public with the ability to inform the public.
- P04 Evaluate and apply current technology related to basic subjects and principles covering pharmacy and health sciences and take part in in-service training seminars.
- P05 Know the risks and evaluation of the use of drugs and other chemicals and safe laboratory practices (GMP).
- P06 Acquire the ability to interpret the findings obtained by qualitative and quantitative measurements and to reach valid scientific results from the data.
- P07 Prepare pharmaceuticals and provide guidance on the use of pharmaceutical products.
- P08 Design research and develop projects related to pharmaceutical products; manage and share the results.
- P09 Be competent to accurately and intelligibly communicate and transfer knowledge about prescription content and pharmaceutical products to the patient / user. The graduates are trained on taking necessary precautions for safe drug usage and encouraging rational drug use, as well as providing consultancy and supervision.
- P10 Work in an interdisciplinary environment. Graduates can cooperate with other professional groups, participate in vocational training and activities, have proper knowledge and communication skills.
- P11 Take part in social responsibility projects related to health. Graduates have awareness on sustainable environment and participate in activities and practices related to their profession.
- P12 Open a community pharmacy, also work in hospital pharmacies, can work in different fields related with pharmaceuticals, cosmetics, medical and herbal products, as well as production and quality control in the pharmaceutical industry. Takes part in the professional development of herself/himself, her/his colleagues and pharmacy students.
- P13 Implements the legal and professional law and ethics as a health professional, in issues concerning public health.
- P14 Knows and applies the processes related to drug design from natural or synthetic sources, as well as development, preparation, analysis and metabolism of drugs in the human body.
Po-Lo Matrix
| LO | P01 | P02 | P03 | P04 | P05 | P06 | P07 | P08 | P09 | P10 | P11 | P12 | P13 | P14 | Average |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L01 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L02 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L03 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L04 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L05 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L06 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L07 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L08 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L09 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L10 | 4 | 4 | 4 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 5 | 4 | 5 | 4.64 |
| L11 | 4 | 4 | 4 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 5 | 4 | 5 | 4.57 |
| L12 | 4 | 4 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 5 | 4 | 5 | 4.64 |
| L13 | 4 | 4 | 4 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 5 | 4 | 5 | 4.57 |
| L14 | 4 | 4 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 5 | 4 | 5 | 4.64 |
| L15 | 4 | 4 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 5 | 4 | 5 | 4.64 |