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TR

PHARMACEUTICAL MICROBIOLOGY

Course
PHAR205 - PHARMACEUTICAL MICROBIOLOGY
Department
Pharmacy - English - Undergraduate
Course Type
Course
Status
Required
Language
English
Credit
4
ECTS
5
T+P+L
3 + 0 + 3
Course Coordinator(s)
Assoc. Prof. Dr. Mümtaz GÜRAN
Prerequisite
-
Keywords

Course Description

This course provides theoretical and practical microbiological knowledge essential for pharmacists. Students will obtain knowledge on saprophytic and pathogenic microorganisms. They will learn the importance of microorganisms, learn the effects of microorganisms on pharmaceutical industry and pharmaceutics produced from microorganisms, obtain knowledge on infections caused by microorganisms and antibiotics that are used for their treatment, handle in-vitro sensitivity tests for antibiotics and assays for microbiological activity, learn and perform the principals of sterilization and disinfection. Pathogenic bacteria, cell structure, virulence factors, biofilms, antimicrobial drugs, mechanisms of action of pharmaceutical agents and antibiotic resistance, introduction to mycology, genetic transfer in bacteria and antimicrobial resistance, microbiome and its role, viruses and parasites, viral diseases, parasitic diseases, and their drugs will also be covered.

PHARMACEUTICAL MICROBIOLOGY

Evaluation Tools (Active Term)

No evaluation items have been defined.

Course outcomes

  1. 01 Identify and taxonomically classify universal/morphological features of micro-organisms such as bacteria, fungi, viruses and parasites.
  2. 02 Evaluate and compare the biological and physiological basis of microbial organisms (bacteria, fungi, viruses, parasites) as well as their different life forms
  3. 03 Assess and apply the basic principles of sterilization / disinfection procedures and equipment.
  4. 04 Explain, compare and contrast important features of microbial pathogenesis, antibiotic sensitivity/resistance mechanisms and mechanism of action of major antibiotics/disinfectants.
  5. 05 Describe the different uses of microorganisms in pharmaceutical industry, environment
  6. 06 Carry out laboratory experiments, coming up with a hypothesis and predicting potential outcomes

Course Syllabus

Week Topic
Week 1 Introduction to course organisation
Week 2 Introduction to Pharmaceutical Microbiology, Prokaryotic and Eukaryotic Microorganisms
Week 3 Bacteria: Structure, Classification, Harms and Benefits
Week 4 Fungi and Viruses: Structure, Classification and General characteristics
Week 5 General characteristics of Parasites and Parasitic Diseases
Week 6 Bacterial metabolism and bacterial growth
Week 7 Revisions
Week 8 Midterm
Week 9 Microbial pathogenesis and Drug targets
Week 10 Sterilization, disinfection, contamination and medical waste management in pharmaceutical industry
Week 11 Infection control: antibiotics and other therapeutics I
Week 12 Infection control: antibiotics and other therapeutics II
Week 13 Pharmaceutical microbiology and its applications in the pharmaceutical industry I
Week 14 Pharmaceutical microbiology and its applications in the pharmaceutical industry II
Week 15 Final Revisions

Reference Books & Course Materials

  1. 01 Denyer S.P., Hodgen N., Gorman B.F., Hugo and Russell's Pharmaceutical Microbiology, Wiley, 8th ed., 2011
  2. 02 Molecular Medical Microbiology, Max Sussmann, 2nd Ed., 2014
  3. 03 Joanne M. Willey, Linda M. Sherwood, Christopher J. Woolverton, Prescott's Microbiology, McGraw Hill, 8th Ed., 2011

Learning Outcomes

  1. L01 Identify and taxonomically classify universal/morphological features of micro-organisms such as bacteria, fungi, viruses and parasites. SOLO 5
  2. L02 Evaluate and compare the biological and physiological basis of microbial organisms (bacteria, fungi, viruses, parasites) as well as their different life forms SOLO 4
  3. L03 Assess and apply the basic principles of sterilization / disinfection procedures and equipment. SOLO 4
  4. L04 Explain, compare and contrast important features of microbial pathogenesis, antibiotic sensitivity/resistance mechanisms and mechanism of action of major antibiotics/disinfectants. SOLO 3
  5. L05 Describe the different uses of microorganisms in pharmaceutical industry, environment SOLO 2
  6. L06 Carry out laboratory experiments, coming up with a hypothesis and predicting potential outcomes SOLO 2

Program Outcomes

  1. P01 Gain the ability to apply the Pharmacy profession.
  2. P02 Interpret the accuracy and reliability of the current theoretical and practical knowledge in the field of pharmacy, as well as being able to follow and evaluate innovations.
  3. P03 Practically apply the knowledge they gain on pharmaceutical sciences. The acquired knowledge and skills allow the graduates to act as the closest health consultant to the public with the ability to inform the public.
  4. P04 Evaluate and apply current technology related to basic subjects and principles covering pharmacy and health sciences and take part in in-service training seminars.
  5. P05 Know the risks and evaluation of the use of drugs and other chemicals and safe laboratory practices (GMP).
  6. P06 Acquire the ability to interpret the findings obtained by qualitative and quantitative measurements and to reach valid scientific results from the data.
  7. P07 Prepare pharmaceuticals and provide guidance on the use of pharmaceutical products.
  8. P08 Design research and develop projects related to pharmaceutical products; manage and share the results.
  9. P09 Be competent to accurately and intelligibly communicate and transfer knowledge about prescription content and pharmaceutical products to the patient / user. The graduates are trained on taking necessary precautions for safe drug usage and encouraging rational drug use, as well as providing consultancy and supervision.
  10. P10 Work in an interdisciplinary environment. Graduates can cooperate with other professional groups, participate in vocational training and activities, have proper knowledge and communication skills.
  11. P11 Take part in social responsibility projects related to health. Graduates have awareness on sustainable environment and participate in activities and practices related to their profession.
  12. P12 Open a community pharmacy, also work in hospital pharmacies, can work in different fields related with pharmaceuticals, cosmetics, medical and herbal products, as well as production and quality control in the pharmaceutical industry. Takes part in the professional development of herself/himself, her/his colleagues and pharmacy students.
  13. P13 Implements the legal and professional law and ethics as a health professional, in issues concerning public health.
  14. P14 Knows and applies the processes related to drug design from natural or synthetic sources, as well as development, preparation, analysis and metabolism of drugs in the human body.

Po-Lo Matrix

LO P01 P02 P03 P04 P05 P06 P07 P08 P09 P10 P11 P12 P13 P14 Average
L01 0 4 4 5 5 4 3 4 4 4 5 3 3 3 3.64
L02 0 0 3 5 4 5 3 4 3 5 5 5 3 4 3.5
L03 3 4 4 4 5 5 5 5 4 5 2 5 3 4 4.14
L04 3 5 5 5 5 5 5 5 4 5 3 5 4 3 4.43
L05 4 5 5 5 4 5 5 5 0 5 5 5 5 5 4.5
L06 4 5 5 5 5 5 5 5 4 5 5 5 3 5 4.71