PHARMACOLOGY-I
- Course
- PHAR210 - PHARMACOLOGY-I
- Department
- Pharmacy - English - Undergraduate
- Course Type
- Course
- Status
- Required
- Language
- English
- Credit
- 4
- ECTS
- 6
- T+P+L
- 4 + 0 + 0
- Course Coordinator(s)
- Dr. Nuran COŞKUN
- Prerequisite
- -
Course Description
The first part of the course, General Pharmacology, is designed to acquaint students with the general aspects of pharmacology and common terminology in pharmacological sciences, along with the basics of drug pharmacokinetics and pharmacodynamics. The second part, Pharmacology of Autonomic Nervous System (ANS), deals with the anatomy and physiology of the peripheral nervous system which is responsible with mainly involuntarily functions of our body. The neurotransmitters of ANS and their receptors are targets for drug action to relieve several clinical conditions, also they involve the actions of many currently used drugs that will be presented in the following courses, Pharmacology II and III. The last part of this course, “Autacoids”, dealt with local hormones that they are involved in many clinical conditions.
PHARMACOLOGY-I
Evaluation Tools (Active Term)
| Item | Type | Weight (%) |
|---|---|---|
| MIDTERM | Midterm | 40 |
| FINAL | Final | 60 |
| Total | 100 | |
Course outcomes
No course outcomes have been defined yet.
Course Syllabus
| Week | Topic |
|---|---|
| Week 1 | Terms and definitions in Pharmacology, Drug nomenclature, drug classification, drug formulations, principles of rational drug, Mechanisms for diffusion and transport, factors affecting drug passage from biological membranes |
| Week 2 | Routes for drug administration, Drug absorption, Drug distribution and binding, methods in estimating binding affinity, apparent volume of distribution and clinical importance |
| Week 3 | Factors affecting drug distribution in the body, |
| Week 4 | Drug elimination, Biotransformation, Clinical concepts for drug clearence |
| Week 5 | Theories for mechanisms of drug effect and concentration-effect relationships |
| Week 6 | Factors affecting drug effectiveness |
| Week 7 | Pharmacogenetics |
| Week 8 | Drug-drug, drug-diet and drug-test interactions |
| Week 9 | Basics of Autonomic Nervous System |
| Week 10 | Parasympathomimetic and parasympatholytic drugs |
| Week 11 | Sympathomimetic and sympatholytic drugs |
| Week 12 | Introduction to Autacoids, Histamine and related drugs, Serotonin and related drugs |
| Week 13 | Drugs related to renin-angiotensin system and kinin peptides |
| Week 14 | Lipid-derived autacoids and related drugs |
| Week 15 | Other autacoids |
Reference Books & Course Materials
- 01 Goodman and Gilman’s The Pharmacological Basis of Therapeutics, Eds: Brunton L.L., Hilal-Dandan R., Knollmann RC, McGrawHill, 13th Edition, 2016
- 02 Basic and Clinical Pharmacology, Ed: Katzung BC. Lange, 14th Edition, 2017
- 03 Basic and Clinical Pharmacology, Ed: Katzung BC, 14th edition, Lange, 2017
- 04 Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Kayaalp O, 13. baskı, Pelikan Kitabevi, 2012
Learning Outcomes
- L01 Clarifying the general concepts in clinical drug effect SOLO 3
- L02 Recognizing the principles and criteria in rational drug therapy SOLO 2
- L03 Explaining the clinical importance of drugs related to autonomic nervous system SOLO 4
- L04 Identifying the effects and their importance of autacoids in various clinical conditions SOLO 2
- L05 Explain the general concepts in clinical drug effect SOLO 4
- L06 Clarify the principles and criteria in rational drug therapy SOLO 3
- L07 Identifying the clinical importance of drugs related to autonomic nervous system SOLO 2
- L08 Describing the effects and their importance of autacoids in various clinical conditions SOLO 3
Program Outcomes
- P01 Gain the ability to apply the Pharmacy profession.
- P02 Interpret the accuracy and reliability of the current theoretical and practical knowledge in the field of pharmacy, as well as being able to follow and evaluate innovations.
- P03 Practically apply the knowledge they gain on pharmaceutical sciences. The acquired knowledge and skills allow the graduates to act as the closest health consultant to the public with the ability to inform the public.
- P04 Evaluate and apply current technology related to basic subjects and principles covering pharmacy and health sciences and take part in in-service training seminars.
- P05 Know the risks and evaluation of the use of drugs and other chemicals and safe laboratory practices (GMP).
- P06 Acquire the ability to interpret the findings obtained by qualitative and quantitative measurements and to reach valid scientific results from the data.
- P07 Prepare pharmaceuticals and provide guidance on the use of pharmaceutical products.
- P08 Design research and develop projects related to pharmaceutical products; manage and share the results.
- P09 Be competent to accurately and intelligibly communicate and transfer knowledge about prescription content and pharmaceutical products to the patient / user. The graduates are trained on taking necessary precautions for safe drug usage and encouraging rational drug use, as well as providing consultancy and supervision.
- P10 Work in an interdisciplinary environment. Graduates can cooperate with other professional groups, participate in vocational training and activities, have proper knowledge and communication skills.
- P11 Take part in social responsibility projects related to health. Graduates have awareness on sustainable environment and participate in activities and practices related to their profession.
- P12 Open a community pharmacy, also work in hospital pharmacies, can work in different fields related with pharmaceuticals, cosmetics, medical and herbal products, as well as production and quality control in the pharmaceutical industry. Takes part in the professional development of herself/himself, her/his colleagues and pharmacy students.
- P13 Implements the legal and professional law and ethics as a health professional, in issues concerning public health.
- P14 Knows and applies the processes related to drug design from natural or synthetic sources, as well as development, preparation, analysis and metabolism of drugs in the human body.
Po-Lo Matrix
| LO | P01 | P02 | P03 | P04 | P05 | P06 | P07 | P08 | P09 | P10 | P11 | P12 | P13 | P14 | Average |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L01 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| L02 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| L03 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| L04 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| L05 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 3 | 3 | 3.86 |
| L06 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L07 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| L08 | 3 | 4 | 4 | 4 | 3 | 3 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 2 | 3.64 |