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TR

IMMUNOLOGY

Course
PHAR208 - IMMUNOLOGY
Department
Pharmacy - English - Undergraduate
Course Type
Course
Status
Required
Language
English
Credit
2
ECTS
4
T+P+L
2 + 0 + 0
Course Coordinator(s)
Asst. Prof. Dr. Vural YILMAZ
Prerequisite
Keywords

Course Description

In this course, the students are introduced to the topics of immunology, antigen and antibody recognition and selection, cellular and humoral immunity, hypersensitivity reactions. Vaccines, vaccine generation, importance and action mechanisms of vaccines are covered as well as transplantation of tissues and organs, methods and possible complications. Antibody development and antibody engineering, immune cell structure/function/sorting and molecular basics and techniques of immunology are covered. The structure of antibodies, T-cell and B-cell receptors, MHC, and their functions are included among topics. V(D)J recombination, its mechanisms and enzymes are discussed as well as the details of somatic hypermutation. Positive and negative selection of immune cells, potential complications and autoimmune diseases that can arise from immune system dysfunction are discussed.

IMMUNOLOGY

Evaluation Tools (Active Term)

Item Type Weight (%)
Project/Quiz Project 20
MidTerm Midterm 40
Final Final 40
Total 100

Course outcomes

  1. 01 By the completion of the course the students should be able to: 1. Be able to understand main components and functions of the immune system.
  2. 02 2. Be able to comprehend relationships between antigens and antibodies.
  3. 03 3. Be able to know basic principles adaptive/innate immunity.
  4. 04 4. Be able to search and interpret multidisciplinary scientific articles.
  5. 05 5. Be able to comprehend the importance and necessity of vaccinations.

Course Syllabus

Week Topic
Week 1 Introduction to Course Organization, Background and Expectations
Week 2 Immunology: An Introduction
Week 3 Elements of the Immune System and their Roles
Week 4 Innate Immunity: An Emphasis on Complement Pathway
Week 5 Principles of Adaptive Immunity
Week 6 Antibody Structure, V(D)J Recombination and Generation of B-cell diversity
Week 7 Overview of The Covered Material - Question& Answer Session
Week 8 Midterm Exam
Week 9 Antigen Recognition by T Lymphocytes and their development
Week 10 Development of B Lymphocytes & B-cell/antibody mediated immunity
Week 11 Failures/ Over-reactions of the Body's Defenses
Week 12 Vaccination to Prevent Infectious Disease
Week 13 Transplantation
Week 14 Revision for Final Exam
Week 15 Final Exam

Reference Books & Course Materials

  1. 01 The Immune System, Peter Parham, 3rd edition, Garland Science, 2009 ISBN: 978-0-8153-4146-8
  2. 02 Janeway's Immunobiology, 7th edition, Kenneth Murphy, Paul Travers, Mark Walport, Garland Science, 2008 ISBN:978-0-8153-4123-9

Learning Outcomes

  1. L01 By the completion of the course the students should be able to: 1. Be able to explain main components and functions of the immune system. SOLO 2
  2. L02 2. Be able to classify relationships between antigens and antibodies. SOLO 2
  3. L03 3. Be able to compare and contrast basic principles adaptive/innate immunity. SOLO 4
  4. L04 4. Be able to search and interpret multidisciplinary scientific articles. SOLO 4
  5. L05 5. Be able to describe the importance and necessity of vaccinations. SOLO 3

Program Outcomes

  1. P01 Gain the ability to apply the Pharmacy profession.
  2. P02 Interpret the accuracy and reliability of the current theoretical and practical knowledge in the field of pharmacy, as well as being able to follow and evaluate innovations.
  3. P03 Practically apply the knowledge they gain on pharmaceutical sciences. The acquired knowledge and skills allow the graduates to act as the closest health consultant to the public with the ability to inform the public.
  4. P04 Evaluate and apply current technology related to basic subjects and principles covering pharmacy and health sciences and take part in in-service training seminars.
  5. P05 Know the risks and evaluation of the use of drugs and other chemicals and safe laboratory practices (GMP).
  6. P06 Acquire the ability to interpret the findings obtained by qualitative and quantitative measurements and to reach valid scientific results from the data.
  7. P07 Prepare pharmaceuticals and provide guidance on the use of pharmaceutical products.
  8. P08 Design research and develop projects related to pharmaceutical products; manage and share the results.
  9. P09 Be competent to accurately and intelligibly communicate and transfer knowledge about prescription content and pharmaceutical products to the patient / user. The graduates are trained on taking necessary precautions for safe drug usage and encouraging rational drug use, as well as providing consultancy and supervision.
  10. P10 Work in an interdisciplinary environment. Graduates can cooperate with other professional groups, participate in vocational training and activities, have proper knowledge and communication skills.
  11. P11 Take part in social responsibility projects related to health. Graduates have awareness on sustainable environment and participate in activities and practices related to their profession.
  12. P12 Open a community pharmacy, also work in hospital pharmacies, can work in different fields related with pharmaceuticals, cosmetics, medical and herbal products, as well as production and quality control in the pharmaceutical industry. Takes part in the professional development of herself/himself, her/his colleagues and pharmacy students.
  13. P13 Implements the legal and professional law and ethics as a health professional, in issues concerning public health.
  14. P14 Knows and applies the processes related to drug design from natural or synthetic sources, as well as development, preparation, analysis and metabolism of drugs in the human body.

Po-Lo Matrix

LO P01 P02 P03 P04 P05 P06 P07 P08 P09 P10 P11 P12 P13 P14 Average
L01 3 4 4 5 4 3 0 3 4 5 5 3 3 3 3.5
L02 4 5 4 4 0 0 0 3 0 5 3 0 3 0 2.21
L03 3 4 0 3 0 0 0 0 0 0 4 3 0 3 1.43
L04 3 5 5 5 5 5 3 5 0 5 5 5 3 5 4.21
L05 4 4 5 5 5 4 5 5 5 5 5 3 5 5 4.64