CANCER BIOLOGY
- Course
- BIOE628 - CANCER BIOLOGY
- Department
- Bioengineering - English - PhD
- Course Type
- Course
- Status
- Required
- Language
- English
- Credit
- 3
- ECTS
- 0
- T+P+L
- 3 + 0 + 0
- Course Coordinator(s)
- -
- Prerequisite
- -
- Keywords
- -
Course Description
-
CANCER BIOLOGY
Evaluation Tools (Active Term)
No evaluation items have been defined.
Course outcomes
- 01 1. To be able to apply the data obtained from basic sciences such as mathematics, physics, chemistry and biology to problems related to all areas of molecular biology and genetics.
- 02 2. Ability to identify, model and produce solutions to all problems related to molecular biology and genetics.
- 03 3. To learn DNA structure, stability, repair mechanisms and chemical carcinogens
- 04 4. Learning transcriptional regulation, epigenetic factors and telomeres
- 05 5. To learn the relationship between cell cycle and cancer, cyclin-dependent kinases and their use in cancer therapy
- 06 6. Learning the relationship between growth factors and cancer, oncogenes, cell signaling systems and cancer formation mechanisms
- 07 7. To learn the relationship between apoptosis and cancer
Course Syllabus
| Week | Topic |
|---|---|
| Week 1 | Overview of Cancer Biology |
| Week 2 | DNA replication and cell cycle |
| Week 3 | Oncogenes, tumor suppressor genes and tumor viruses |
| Week 4 | Oncogenes, tumor suppressor genes and tumor viruses |
| Week 5 | Signal pathways involved in cancer |
| Week 6 | Signal pathways involved in cancer |
| Week 7 | Midterm Exam |
| Week 8 | Midterm Exam |
| Week 9 | P53 and Apoptosis (Programmed cell death) |
| Week 10 | Cell immortality and Tumorization |
| Week 11 | Biology of Angiogenesis |
| Week 12 | Metastasis and Epithelial Mesenchymal Transition |
| Week 13 | Metastasis and Epithelial Mesenchymal Transition |
| Week 14 | Final |
| Week 15 | Final |
Reference Books & Course Materials
- 01 1. Taghian, A.G.; Smith, B.L.; Erban, J.K., Breast Cancer (2016). Demosmedical, New York, 356pp
- 02 2. Chmielowski, Bartosz; Territo, Mary, Manual of Clinical Oncology (2017). Lippincott Williams & Wilkins (LWW), 900 pp
- 03 3. Stella Pelengaris, Mike Khan, The Molecular Biology of Cancer: A Bridge from Bench to Bedside (2013)
Learning Outcomes
No learning outcomes have been defined.
Program Outcomes
No program outcomes have been defined.
Po-Lo Matrix
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