IMMUNOLOGY

Course Description

In this course, the students are introduced to the topics of immunology, antigen and antibody recognition and selection, cellular and humoral immunity, hypersensitivity reactions. Vaccines, vaccine generation, importance and action mechanisms of vaccines are covered as well as transplantation of tissues and organs, methods and possible complications. Antibody development and antibody engineering, immune cell structure/function/sorting and molecular basics and techniques of immunology are covered. The structure of antibodies, T-cell and B-cell receptors, MHC, and their functions are included among topics. V(D)J recombination, its mechanisms and enzymes are discussed as well as the details of somatic hypermutation. Positive and negative selection of immune cells, potential complications and autoimmune diseases that can arise from immune system dysfunction are discussed.

IMMUNOLOGY

Evaluation Tools (Active Term)

Course outcomes

1. 01 By the completion of the course the students should be able to: 1. Be able to understand main components and functions of the immune system.
2. 02 2. Be able to comprehend relationships between antigens and antibodies.
3. 03 3. Be able to know basic principles adaptive/innate immunity.
4. 04 4. Be able to search and interpret multidisciplinary scientific articles.
5. 05 5. Be able to comprehend the importance and necessity of vaccinations.

Course Syllabus

Reference Books & Course Materials

1. 01 The Immune System, Peter Parham, 3rd edition, Garland Science, 2009 ISBN: 978-0-8153-4146-8
2. 02 Janeway's Immunobiology, 7th edition, Kenneth Murphy, Paul Travers, Mark Walport, Garland Science, 2008 ISBN:978-0-8153-4123-9

Learning Outcomes

1. L01 By the completion of the course the students should be able to: 1. Be able to explain main components and functions of the immune system. SOLO 2
2. L02 2. Be able to classify relationships between antigens and antibodies. SOLO 2
3. L03 3. Be able to compare and contrast basic principles adaptive/innate immunity. SOLO 4
4. L04 4. Be able to search and interpret multidisciplinary scientific articles. SOLO 4
5. L05 5. Be able to describe the importance and necessity of vaccinations. SOLO 3

Program Outcomes

1. P01 PO1: To identify and use theoretical and applied knowledge as well as up-to-date/cutting edge laboratory techniques and analyses methods in the field of molecular biology and genetics.
2. P02 PO2: To identify problems related to molecular biology and genetics.
3. P03 PO3: To design and conduct experiments through hypothesis driven scientific research; and to analyze and interpret data to find solutions to molecular biology and genetics related problems.
4. P04 PO4: To work independently and as part of research group in a multidisciplinary team setting
5. P05 PO5: To apply the principles of scientific research ethics and academic integrity
6. P06 PO6: To interpret, explain and present primary scientific literature and novel findings in oral, written and visual presentation formats
7. P07 PO7: To evaluate experimental data and theoretical findings by using critical and analytical thinking techniques.
8. P08 PO8: To use the currently acceptable process of preparing research proposals and manuscripts for publishing in scientific journals.
9. P09 PO9: To apply the principles of molecular biology and genetics in generating/finding solutions to social problems / issues.
10. P10 PO10: To identify and implement environmental and laboratory safety procedures.
11. P11 PO11: To identify and apply the necessary professional skill set in projects and jobs involving independent and competitive careers in academia, industrial, medical or clinical research, science education, scientific writing and communication, health care, health care policy and civil service.

Po-Lo Matrix