STEM CELL BIOLOGY
- Course
- MBGE473 - STEM CELL BIOLOGY
- Department
- Basic Sciences and Humanities
- Course Type
- Course
- Status
- Required
- Language
- English
- Credit
- 3
- ECTS
- 7
- T+P+L
- 3 + 0 + 0
- Course Coordinator(s)
- -
- Prerequisite
- -
Course Description
The course provides students with detailed information on the fundamentals of stem cell biology, different types of stem cells (i.e. embryonic, fetal, adult and inducible pluripotent stem cells) and their clinical applications. Properties of stem cells (i.e. multi-potency, differentiation and so on) are outlined. In this course, different types of stem cells; their sources, properties and applications in regenerative medicine will be described. Interactions between stem cells and their environment (i.e. niches) are emphasized. Current research in the field of stem cell therapy is highlighted. The advantages and disadvantages of the current stem cell therapy are outlined and peer reviewed articles are discussed.
STEM CELL BIOLOGY
Evaluation Tools (Active Term)
No evaluation items have been defined.
Course outcomes
No course outcomes have been defined yet.
Course Syllabus
| Week | Topic |
|---|---|
| Week 1 | Course Introduction |
| Week 2 | Introduction to Stem cells |
| Week 3 | Introduction to Development |
| Week 4 | Pluripotency and Reprogramming part 1 |
| Week 5 | Pluripotency and Reprogramming part 2 |
| Week 6 | Adult Stem Cells and Regeneration |
| Week 7 | Revision Sessions |
| Week 8 | Midterm Exam |
| Week 9 | Midterm Exam |
| Week 10 | Differentiation and Stem Cell Niches |
| Week 11 | Clinical Applications of Stem cells |
| Week 12 | Quiz |
| Week 13 | Stem Cell Research Ethical Perspectives |
| Week 14 | Revision Sessions |
| Week 15 | Final Exam |
Reference Books & Course Materials
- 01 Essentials of Stem Cell Biology
- 02 StemBook
- 03 Progenitor Cells: methods and protocols
Learning Outcomes
- L01 LO1: Outline the basics of the stem cell biology SOLO 0
- L02 LO2: Define and explain the establishment of pluripotency and reprogramming in vitro SOLO 0
- L03 LO3: Summarize brief understanding and examples of the clinical applications of stem cells SOLO 0
- L04 LO4: Define and discuss the ethical perspectives of the stem cell research SOLO 0
Program Outcomes
- P01 PO1: To identify and use theoretical and applied knowledge as well as up-to-date/cutting edge laboratory techniques and analyses methods in the field of molecular biology and genetics.
- P02 PO2: To identify problems related to molecular biology and genetics.
- P03 PO3: To design and conduct experiments through hypothesis driven scientific research; and to analyze and interpret data to find solutions to molecular biology and genetics related problems.
- P04 PO4: To work independently and as part of research group in a multidisciplinary team setting
- P05 PO5: To apply the principles of scientific research ethics and academic integrity
- P06 PO6: To interpret, explain and present primary scientific literature and novel findings in oral, written and visual presentation formats
- P07 PO7: To evaluate experimental data and theoretical findings by using critical and analytical thinking techniques.
- P08 PO8: To use the currently acceptable process of preparing research proposals and manuscripts for publishing in scientific journals.
- P09 PO9: To apply the principles of molecular biology and genetics in generating/finding solutions to social problems / issues.
- P10 PO10: To identify and implement environmental and laboratory safety procedures.
- P11 PO11: To identify and apply the necessary professional skill set in projects and jobs involving independent and competitive careers in academia, industrial, medical or clinical research, science education, scientific writing and communication, health care, health care policy and civil service.
Po-Lo Matrix
| LO | P01 | P02 | P03 | P04 | P05 | P06 | P07 | P08 | P09 | P10 | P11 | Average |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L01 | 4 | 5 | 3 | 1 | 3 | 4 | 3 | 1 | 4 | 1 | 4 | 3 |
| L02 | 4 | 4 | 3 | 1 | 3 | 4 | 3 | 0 | 2 | 1 | 3 | 2.55 |
| L03 | 3 | 5 | 3 | 1 | 4 | 3 | 2 | 1 | 4 | 1 | 3 | 2.73 |
| L04 | 1 | 3 | 1 | 1 | 5 | 3 | 3 | 1 | 5 | 1 | 3 | 2.45 |