MOLECULAR BIOLOGY II

Course Description

The course provides both theoretical and practical in-depth explanations of several molecular biology concepts and laboratory techniques. This course should be taken after MBGE302 and with MBGE403. The main topics include the study of the characteristics, functions, biogenesis and molecular detection methods of small non-coding RNAs such as miRNAs and piRNA and long non-coding RNAs. Students will learn how to design miRNAs, the study of amino acids, protein structure, folding and degradation, the characteristics of enzymes, enzyme structure, and function. Enzyme kinetics will be discussed including how to compute for Km, Vmax and how to use the Michaelis-Menten equation. Antibody characteristics, function, design, and production will also be analyzed followed by the history, development, applications of several transgenic animal models.

MOLECULAR BIOLOGY II

Evaluation Tools (Active Term)

Course outcomes

No course outcomes have been defined yet.

Course Syllabus

Reference Books & Course Materials

1. 01 Lehninger, Principles of Biochemistry 6th Edition
2. 02 Molecular Biology of the Cell (Bruce Alberts)
3. 03 Pubmed

Learning Outcomes

1. L01 LO1: Theorize basic concepts of molecular genetics SOLO 5
2. L02 LO2: Discuss molecular mechanisms of phenotypes, including cell cycle, development, enzyme kinetics and disease SOLO 5
3. L03 LO3: Examine molecular biology concepts in relation to recent developments in the field SOLO 3

Program Outcomes

1. P01 PO1: To identify and use theoretical and applied knowledge as well as up-to-date/cutting edge laboratory techniques and analyses methods in the field of molecular biology and genetics.
2. P02 PO2: To identify problems related to molecular biology and genetics.
3. P03 PO3: To design and conduct experiments through hypothesis driven scientific research; and to analyze and interpret data to find solutions to molecular biology and genetics related problems.
4. P04 PO4: To work independently and as part of research group in a multidisciplinary team setting
5. P05 PO5: To apply the principles of scientific research ethics and academic integrity
6. P06 PO6: To interpret, explain and present primary scientific literature and novel findings in oral, written and visual presentation formats
7. P07 PO7: To evaluate experimental data and theoretical findings by using critical and analytical thinking techniques.
8. P08 PO8: To use the currently acceptable process of preparing research proposals and manuscripts for publishing in scientific journals.
9. P09 PO9: To apply the principles of molecular biology and genetics in generating/finding solutions to social problems / issues.
10. P10 PO10: To identify and implement environmental and laboratory safety procedures.
11. P11 PO11: To identify and apply the necessary professional skill set in projects and jobs involving independent and competitive careers in academia, industrial, medical or clinical research, science education, scientific writing and communication, health care, health care policy and civil service.

Po-Lo Matrix