MOLECULAR GENETICS

Course Description

In the course, qualitative and quantitative levels of gene expressions are explained in diploid and haploid organisms. The main approach of the course is to introduce the basics of inheritance on genes and genomes by using Mendelian genetics and non-Mendelian genetics. In addition, the hereditary features of extranuclear inheritance and sex determination in various organisms are examined within the scope of this course. Chromosomal mutation types and their inherited transmission will be discussed. At the end of the course, it is aimed that the student will be able to make pedigree drawings, which is the classical gene mapping method, as an introduction to modern mapping methods with the knowledge student has acquired in the face of hereditary problems.

MOLECULAR GENETICS

Evaluation Tools (Active Term)

Course outcomes

No course outcomes have been defined yet.

Course Syllabus

Reference Books & Course Materials

1. 01 Molecular Biology Of The Cell - Bruce Albert et al.
2. 02 Molecular biology of the gene - James Watson et al.
3. 03 Essential Genes - Benjamin Lewin
4. 04 Human Genetics (12th Edition) – Ricki Lewis

Learning Outcomes

1. L01 LO1: Describe the basic laws and mechanisms governing transmission genetics. SOLO 0
2. L02 LO2: Predict inheritance modes by studying pedigrees SOLO 0
3. L03 LO3: Describe the fundamental processes in molecular genetics, including DNA replication, mutation, recombination, transcription, and translation; SOLO 0
4. L04 LO4: Distinguish between prokaryotic and eukaryotic systems with respect to gene regulation; SOLO 0

Program Outcomes

1. P01 PO1: To identify and use theoretical and applied knowledge as well as up-to-date/cutting edge laboratory techniques and analyses methods in the field of molecular biology and genetics.
2. P02 PO2: To identify problems related to molecular biology and genetics.
3. P03 PO3: To design and conduct experiments through hypothesis driven scientific research; and to analyze and interpret data to find solutions to molecular biology and genetics related problems.
4. P04 PO4: To work independently and as part of research group in a multidisciplinary team setting
5. P05 PO5: To apply the principles of scientific research ethics and academic integrity
6. P06 PO6: To interpret, explain and present primary scientific literature and novel findings in oral, written and visual presentation formats
7. P07 PO7: To evaluate experimental data and theoretical findings by using critical and analytical thinking techniques.
8. P08 PO8: To use the currently acceptable process of preparing research proposals and manuscripts for publishing in scientific journals.
9. P09 PO9: To apply the principles of molecular biology and genetics in generating/finding solutions to social problems / issues.
10. P10 PO10: To identify and implement environmental and laboratory safety procedures.
11. P11 PO11: To identify and apply the necessary professional skill set in projects and jobs involving independent and competitive careers in academia, industrial, medical or clinical research, science education, scientific writing and communication, health care, health care policy and civil service.

Po-Lo Matrix