MOLECULAR BIOLOGY I

Course Description

The course provides both theoretical and practical in-depth explanations of several molecular biology concepts and laboratory techniques. In this course, the analysis of genetic transfers and gene mutations of eukaryotic cells will be detailed, and DNA repair mechanisms will be taught. In addition, mutagens and epigenetics will be covered in this course and extrachromosomal replicons, diseases related to mitochondrial DNA will be examined. Structure and function analysis of various enzymes used in molecular biology, DNA/RNA purification, PCR and its types, primer design, DNA cloning, DNA recombination, design of plasmid and mammalian vectors, DNA fragmentation, and understanding of DNA sequencing methods are the main topics of this course. This course must be taken in conjunction with MBGE304-Molecular Biology Lab I.

MOLECULAR BIOLOGY I

Evaluation Tools (Active Term)

No evaluation items have been defined.

Course outcomes

No course outcomes have been defined yet.

Course Syllabus

Reference Books & Course Materials

1. 01 Lehninger; Principles of Biochemistry 6th Edition, Molecular Biology of the Cell (Bruce Alberts)
2. 02 https://www.uniprot.org/
3. 03 https://www.rcsb.org/
4. 04 https://www.ncbi.nlm.nih.gov/protein/

Learning Outcomes

1. L01 Explain the hypothetico-deductive method SOLO 0
2. L02 Define cell theory SOLO 0
3. L03 Explain the macromolecules of the cell SOLO 0
4. L04 Discuss the structure and the functions of the enzymes SOLO 0

Program Outcomes

1. P01 PO1: To identify and use theoretical and applied knowledge as well as up-to-date/cutting edge laboratory techniques and analyses methods in the field of molecular biology and genetics.
2. P02 PO2: To identify problems related to molecular biology and genetics.
3. P03 PO3: To design and conduct experiments through hypothesis driven scientific research; and to analyze and interpret data to find solutions to molecular biology and genetics related problems.
4. P04 PO4: To work independently and as part of research group in a multidisciplinary team setting
5. P05 PO5: To apply the principles of scientific research ethics and academic integrity
6. P06 PO6: To interpret, explain and present primary scientific literature and novel findings in oral, written and visual presentation formats
7. P07 PO7: To evaluate experimental data and theoretical findings by using critical and analytical thinking techniques.
8. P08 PO8: To use the currently acceptable process of preparing research proposals and manuscripts for publishing in scientific journals.
9. P09 PO9: To apply the principles of molecular biology and genetics in generating/finding solutions to social problems / issues.
10. P10 PO10: To identify and implement environmental and laboratory safety procedures.
11. P11 PO11: To identify and apply the necessary professional skill set in projects and jobs involving independent and competitive careers in academia, industrial, medical or clinical research, science education, scientific writing and communication, health care, health care policy and civil service.

Po-Lo Matrix