GENETICS AND PERSONALIZED MEDICINE

Course Description

Personalized medicine and pharmacogenetics both promise exciting new developments in healthcare; hence this course aims to allow students to explore the potential of the aforementioned topics while also taking a closer look at genetics, the human genome, genome and exome sequencing, pharmacogenetic tests and a review of current literature. The course also aims to focus on the use of personalized medicine in different diseases including infectious diseases, cancer and neurological disorders. Topics covered include molecular diagnostic tools that are widely used in personalized medicine, importance of variations, genotyping, haplotyping and biomarkers in personalized medicine, basics of pharmacogenetics and focus on personalized medicine.

GENETICS AND PERSONALIZED MEDICINE

Evaluation Tools (Active Term)

Course outcomes

No course outcomes have been defined yet.

Course Syllabus

Reference Books & Course Materials

1. 01 Genomics and Personalized Medicine: What Everyone Needs to Know , Michael Snyder , Oxford University Press, ISBN : 978-0190234768
2. 02 Thompson & Thompson Genetics and Genomics in Medicine , Ronald Cohn & Stephen Scherer & Ada Hamosh , Elsevier , 2023 , ISBN : 978-0323547628
3. 03 Personalised Medicine, Individual Choice and the Common Good , Britta van Beers , Sigrid Sterckx , Donna Dickenson , Cambridge University Press , 2019 , ISBN : 978-1108473910

Learning Outcomes

1. L01 Explain DNA analysis & discuss the importance of whole genome sequencing and exome sequencing. SOLO 0
2. L02 Examine importance of variations in terms of personalized medicine SOLO 0
3. L03 Describe pharmacokinetics and pharmacodynamics SOLO 0
4. L04 Discuss the use of treatment stratification and rational drug design for patients SOLO 0

Program Outcomes

1. P01 PO1: To identify and use theoretical and applied knowledge as well as up-to-date/cutting edge laboratory techniques and analyses methods in the field of molecular biology and genetics.
2. P02 PO2: To identify problems related to molecular biology and genetics.
3. P03 PO3: To design and conduct experiments through hypothesis driven scientific research; and to analyze and interpret data to find solutions to molecular biology and genetics related problems.
4. P04 PO4: To work independently and as part of research group in a multidisciplinary team setting
5. P05 PO5: To apply the principles of scientific research ethics and academic integrity
6. P06 PO6: To interpret, explain and present primary scientific literature and novel findings in oral, written and visual presentation formats
7. P07 PO7: To evaluate experimental data and theoretical findings by using critical and analytical thinking techniques.
8. P08 PO8: To use the currently acceptable process of preparing research proposals and manuscripts for publishing in scientific journals.
9. P09 PO9: To apply the principles of molecular biology and genetics in generating/finding solutions to social problems / issues.
10. P10 PO10: To identify and implement environmental and laboratory safety procedures.
11. P11 PO11: To identify and apply the necessary professional skill set in projects and jobs involving independent and competitive careers in academia, industrial, medical or clinical research, science education, scientific writing and communication, health care, health care policy and civil service.

Po-Lo Matrix