CELL BIOLOGY
- Course
- MBGE201 - CELL BIOLOGY
- Department
- Molecular Biology and Genetics - English - Undergraduate
- Course Type
- Course
- Status
- Required
- Language
- English
- Credit
- 4
- ECTS
- 8
- T+P+L
- 3 + 0 + 2
- Course Coordinator(s)
- Asst. Prof. Dr. Çiçek TOPÇU
- Prerequisite
- -
Course Description
This course aims to provide a general introduction to molecular cell biology to demonstrate how molecular cell biology explains cell function at the level of an individual cell, and as part of a tissue or organism. Topics include cellular communication, growth, interactions, division and cell death. Insight into how cells produce and export proteins and how external material is endocytozed will be covered. Intracellular compartments of eukaryotes will be described in detail. Structure and function of membrane-bounded organelles, secretory and vesicular transport, cytoskeleton and cell movement, extracellular matrix, tissue and tissue types, connective tissues, hematopoietic and non-hematopoietic cells will be discussed in detail. The course includes a laboratory module where you will analyze how cells behave in a cell culture dish.
CELL BIOLOGY
Evaluation Tools (Active Term)
| Item | Type | Weight (%) |
|---|---|---|
| Final Exam | Final | 40 |
| Midterm Exam | Midterm | 30 |
| Quiz | Quiz | 10 |
| Lab Report 1 | Project | 5 |
| Lab Report 2 | Project | 5 |
| Lab Report 3 | Project | 5 |
| Lab Exam | Project | 5 |
| Total | 100 | |
Course outcomes
- 01 Describe DNA, RNA, Protein, Genome, chromosome.
- 02 Explain cell membrane and how cells transport materials in and out through the membrane.
- 03 Explain internal organisation of the cell, the organelles and their functions.
- 04 Have the Knowledge of how and when cells divide.
- 05 Have the ability to inspect cells under microscope
- 06 laborate on laboratory techniques: pipeting, calculations, introduction to laboratory equipment and lab safety, sterile technique.
- 07 Elaborate on current molecular biology techniques used in cell research.
Course Syllabus
| Week | Topic |
|---|---|
| Week 1 | Introduction to Cell Biology |
| Week 2 | The Cell Membrane Part 1 |
| Week 3 | The Cell Membrane Part 2 |
| Week 4 | Organelles Part 1 |
| Week 5 | Organelles Part 2 |
| Week 6 | The Cytoskeleton |
| Week 7 | Cell Junctions and Adhesion Part 1, Quiz 1 |
| Week 8 | Cell Junctions and Adhesion Part 2 |
| Week 9 | Midterm Exam |
| Week 10 | The Extracellular Matrix |
| Week 11 | Connective Tissue |
| Week 12 | Apoptosis, Necrosis |
| Week 13 | Autophagy and Proteasomal Degradation |
| Week 14 | Secretory Pathways |
| Week 15 | Autophagy and Proteasomal Degradation |
Reference Books & Course Materials
- 01 Thomas Pollard, William Earnshaw, Jennifer Lippincott-Schwartz. Cell Biology (2nd Ed.) Saunders Elsevier 2008, ISBN 1416022554
Learning Outcomes
- L01 Apply the most advanced and current experimental techniques in genetic engineering, molecular biology and molecular genetics SOLO 0
- L02 Perform and defend the work safety rules SOLO 0
- L03 Describe scientific processes; critique; design experiments and ask questions leading to theorizing SOLO 0
- L04 Review and interpret the current worldwide literature in molecular biology and genetics SOLO 0
Program Outcomes
- P01 PO1: To identify and use theoretical and applied knowledge as well as up-to-date/cutting edge laboratory techniques and analyses methods in the field of molecular biology and genetics.
- P02 PO2: To identify problems related to molecular biology and genetics.
- P03 PO3: To design and conduct experiments through hypothesis driven scientific research; and to analyze and interpret data to find solutions to molecular biology and genetics related problems.
- P04 PO4: To work independently and as part of research group in a multidisciplinary team setting
- P05 PO5: To apply the principles of scientific research ethics and academic integrity
- P06 PO6: To interpret, explain and present primary scientific literature and novel findings in oral, written and visual presentation formats
- P07 PO7: To evaluate experimental data and theoretical findings by using critical and analytical thinking techniques.
- P08 PO8: To use the currently acceptable process of preparing research proposals and manuscripts for publishing in scientific journals.
- P09 PO9: To apply the principles of molecular biology and genetics in generating/finding solutions to social problems / issues.
- P10 PO10: To identify and implement environmental and laboratory safety procedures.
- P11 PO11: To identify and apply the necessary professional skill set in projects and jobs involving independent and competitive careers in academia, industrial, medical or clinical research, science education, scientific writing and communication, health care, health care policy and civil service.
Po-Lo Matrix
| LO | P01 | P02 | P03 | P04 | P05 | P06 | P07 | P08 | P09 | P10 | P11 | Average |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L01 | 4 | 4 | 4 | 3 | 5 | 3 | 3 | 3 | 4 | 3 | 3 | 3.55 |
| L02 | 4 | 4 | 4 | 3 | 3 | 4 | 3 | 3 | 3 | 5 | 3 | 3.55 |
| L03 | 5 | 4 | 3 | 2 | 3 | 3 | 5 | 4 | 3 | 4 | 2 | 3.45 |
| L04 | 4 | 4 | 3 | 3 | 4 | 5 | 4 | 3 | 4 | 4 | 2 | 3.64 |