INTRODUCTION TO MOLECULAR BIOLOGY AND GENETICS

Course Description

The main objectives of the course are to introduce the main concepts of molecular biology and genetics and to provide hands on experience in research techniques. This course emphasizes basic principle and historical development of the molecular biology and genetics, cell biology, universal futures of cells, laboratory guidelines and laboratory safety. Cell cycle and division and cellular transport mechanisms of molecules are discussed. In addition, the central dogma that the basic of genetic is mentioned in the course. The molecular mechanisms of DNA replication, repair, transcription, protein synthesis, and gene regulation. During this course up to date methods in molecular biology and genetics and scientific methodology will be covered.

INTRODUCTION TO MOLECULAR BIOLOGY AND GENETICS

Evaluation Tools (Active Term)

Course outcomes

1. 01 Identify the scientific research and essays.
2. 02 Describe DNA, RNA, Protein, Genome, chromosome, Central Dogma.
3. 03 Explain the scientific methodology
4. 04 Explain internal organisation of the cell, membrane structure, cellular compartments
5. 05 List the universal features of cells.
6. 06 Explain how cells read the genome from DNA to protein.
7. 07 Summarize how chemistry comes to life.
8. 08 Summarize DNA and Chromosome structure and function, genome, genetic diversity of genomes.
9. 09 Elaborate on laboratory techniques: pipeting, calculations, introduction to laboratory equipment and lab safety, sterile technique.
10. 10 Elaborate on transfection of cells with GFP.

Course Syllabus

Reference Books & Course Materials

1. 01 Bruce Alberts, Alexander Johnson, Julion Lewis& Martin Raff. Molecular Biology of the Cell (5th edition). Garland Science, 2007. ISBN-13: 978-0815341055
2. 02 David P. Clark, Nanette J. PazderniK. Academic Cell, Molecular Biology (2nd Edition) Elsevier ISBN:978-0-12-378594-7
3. 03 D. K.. Kar Dipak Kumar Kar,S. Halder (Authors). Cell Biology Genetics Molecular Biology. ISBN-13 : 978-8173815980
4. 04 Genetics: From Genes to Genomes 7th Edition, Michael Goldberg and Janice Fischer and Leroy Hood and Leland Hartwell

Learning Outcomes

1. L01 Identify the scientific research and essays. SOLO 2
2. L02 Describe DNA, RNA, Protein, Genome, chromosome, Central Dogma. SOLO 3
3. L03 Explain the scientific methodology. SOLO 4
4. L04 Explain internal organisation of the cell, membrane structure, cellular compartments. SOLO 4
5. L05 List the universal features of cells. SOLO 3
6. L06 Explain how cells read the genome from DNA to protein. SOLO 4
7. L07 Summarize how chemistry comes to life. SOLO 4
8. L08 Summarize DNA and Chromosome structure and function, genome, genetic diversity of genomes. SOLO 4
9. L09 Elaborate on laboratory techniques: pipeting, calculations, introduction to laboratory equipment and lab safety, sterile technique. SOLO 5
10. L10 Elaborate on transfection of cells with GFP. SOLO 5

Program Outcomes

1. P01 PO1: To identify and use theoretical and applied knowledge as well as up-to-date/cutting edge laboratory techniques and analyses methods in the field of molecular biology and genetics.
2. P02 PO2: To identify problems related to molecular biology and genetics.
3. P03 PO3: To design and conduct experiments through hypothesis driven scientific research; and to analyze and interpret data to find solutions to molecular biology and genetics related problems.
4. P04 PO4: To work independently and as part of research group in a multidisciplinary team setting
5. P05 PO5: To apply the principles of scientific research ethics and academic integrity
6. P06 PO6: To interpret, explain and present primary scientific literature and novel findings in oral, written and visual presentation formats
7. P07 PO7: To evaluate experimental data and theoretical findings by using critical and analytical thinking techniques.
8. P08 PO8: To use the currently acceptable process of preparing research proposals and manuscripts for publishing in scientific journals.
9. P09 PO9: To apply the principles of molecular biology and genetics in generating/finding solutions to social problems / issues.
10. P10 PO10: To identify and implement environmental and laboratory safety procedures.
11. P11 PO11: To identify and apply the necessary professional skill set in projects and jobs involving independent and competitive careers in academia, industrial, medical or clinical research, science education, scientific writing and communication, health care, health care policy and civil service.

Po-Lo Matrix