BIOCHEMISTRY

Course Description

The objective of this course is to develop a fundamental understanding of the structures, functions, and interactions of proteins, carbohydrates, lipids, and nucleic acids. The way these molecules mediate biochemical processes in living systems are also studied. In addition, topics also include organic functional groups, the biological role of water, acid-base chemistry and buffers, enzymes and enzyme kinetics, bioenergetics, biological catalysis and biological membranes and cellular transport. The topic also includes the broad understanding of chemical events in living systems in terms of metabolism and structure-function relationships of biologically important molecules. It covers information about catabolic and anabolic pathways of metabolism involving carbohydrates, lipids, amino acids, nitrogenous bases and transfers in biological systems.

BIOCHEMISTRY

Evaluation Tools (Active Term)

Course outcomes

1. 01 Identify (2) and use (3) basis for the molecular structure of different biochemical compounds
2. 02 Explain (4) protein structures and describe (3) the stabilization of these structures
3. 03 Describe (3) the structure and mechanism of representative enzymes in biochemical pathways
4. 04 Interpret (4) plots of enzyme kinetic data.
5. 05 Developed (5) the skills to accumulate, integrate and apply (4) biochemical information in their own field of study.

Course Syllabus

Reference Books & Course Materials

1. 01 Biochemistry, 6th edition Lehninger Principles of Biochemistry by Cox & Nelson,Published by: W.H. Freeman, November 21, 2012 (ISBN: 9781464109621)
2. 02 Pratt, Cornely: “Essential Biochemistry, 2nd Edition”, Wiley, John & Sons, Incorporated (January 12, 2011)(ISBN: 0470504773)
3. 03 Voet, D., Voet, J., and Pratt, C.W. Fundamentals of Biochemistry: Life at the Molecular Level, Wiley; 4th Edition (January 18, 2012) (ISBN: 978-1118129180)
4. 04 Lecture Notes

Learning Outcomes

1. L01 Identify (2) and use (3) basis for the molecular structure of different biochemical compounds
2. L02 Explain (4) protein structures and describe (3) the stabilization of these structures
3. L03 Describe (3) the structure and mechanism of representative enzymes in biochemical pathways
4. L04 Interpret (4) plots of enzyme kinetic data.
5. L05 Developed (5) the skills to accumulate, integrate and apply (4) biochemical information in their own field of study.

Program Outcomes

1. P01 PO1: To identify and use theoretical and applied knowledge as well as up-to-date/cutting edge laboratory techniques and analyses methods in the field of molecular biology and genetics.
2. P02 PO2: To identify problems related to molecular biology and genetics.
3. P03 PO3: To design and conduct experiments through hypothesis driven scientific research; and to analyze and interpret data to find solutions to molecular biology and genetics related problems.
4. P04 PO4: To work independently and as part of research group in a multidisciplinary team setting
5. P05 PO5: To apply the principles of scientific research ethics and academic integrity
6. P06 PO6: To interpret, explain and present primary scientific literature and novel findings in oral, written and visual presentation formats
7. P07 PO7: To evaluate experimental data and theoretical findings by using critical and analytical thinking techniques.
8. P08 PO8: To use the currently acceptable process of preparing research proposals and manuscripts for publishing in scientific journals.
9. P09 PO9: To apply the principles of molecular biology and genetics in generating/finding solutions to social problems / issues.
10. P10 PO10: To identify and implement environmental and laboratory safety procedures.
11. P11 PO11: To identify and apply the necessary professional skill set in projects and jobs involving independent and competitive careers in academia, industrial, medical or clinical research, science education, scientific writing and communication, health care, health care policy and civil service.

Po-Lo Matrix