BIOMATERIALS AND DRUG DELIVERY
- Course
- BIOE225 - BIOMATERIALS AND DRUG DELIVERY
- Department
- Bioengineering - English - Undergraduate
- Course Type
- Course
- Status
- Required
- Language
- English
- Credit
- 3
- ECTS
- 7
- T+P+L
- 3 + 0 + 0
- Course Coordinator(s)
- Asst. Prof. Dr. Nihal BAYIR
- Prerequisite
Course Description
The objective is to develop a fundamental understanding of the definitions, classifications, properties and benefits of biomaterials. This course focuses on the fundamental understanding of implantable materials with respect to their design, analysis and use in human health. This course also includes evaluation of biomedical use, applications and biocompatibilities of biomaterials and provides the basic understanding of the controlled drug delivery systems and introduction to drug targeting. The course also includes the fundamentals of materials synthesis/fabrication, methods of characterisation/analysis, interactions between materials with tissues, quantitative analysis of material properties and how materials are used to impact human health. Also, It covers the application of engineering principles for designing and understanding the delivery of therapeutics.
BIOMATERIALS AND DRUG DELIVERY
Evaluation Tools (Active Term)
| Item | Type | Weight (%) |
|---|---|---|
| Midterm Exam | Midterm | 50 |
| Final Exam | Final | 50 |
| Total | 100 | |
Course outcomes
- 01 To classify (3) the classes of biomaterials used in biomedical applications, and explain (4) the various factors (materials properties, biologic response, etc.) that define the utility and applications of these materials.
- 02 to Clarify (3) the knowledge of science and engineering to topics such as processing, characterization, and end use of biomaterials.
- 03 Predict (5) the material selection and structure- function relations
- 04 Constructing (4) ethical responsibility related to develop and use of biomaterials in clinical applications.
- 05 -to define (3) traditional and novel technologies on drug delivery systems.
- 06 Design (5) a project on a current biomaterial application, comparing the currently used materials, national and global industrial analysis and preparation of prersentation with applications
Course Syllabus
| Week | Topic |
|---|---|
| Week 1 | General Introduction to Biomaterial and Drug Delivery |
| Week 2 | Introduction to Biomaterials (Definition, Classification) |
| Week 3 | Mechanical and Physical properties of Materials |
| Week 4 | Biometals |
| Week 5 | Bioceramics |
| Week 6 | Biocomposites |
| Week 7 | Biopolymers |
| Week 8 | Midterm Exam |
| Week 9 | Drug Delivery Systems |
| Week 10 | Controlled Drug delivery systems |
| Week 11 | Release Kinetics |
| Week 12 | Kinetic models |
| Week 13 | Biomaterials for drug delivery |
| Week 14 | Revision |
| Week 15 | Final Exams |
Reference Books & Course Materials
- 01 Biomaterials - Temenoff and Mikos (Pearson Prentice Hall; ISBN 0-13-009710-1)
- 02 Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids, Ram I. Mahato, CRC Press, ISBN 9780849323348
- 03 Lecture Notes
Learning Outcomes
- L01 To classify (3) the classes of biomaterials used in biomedical applications, and explain (4) the various factors (materials properties, biologic response, etc.) that define the utility and applications of these materials. SOLO 3.5
- L02 to Clarify (3) the knowledge of science and engineering to topics such as processing, characterization, and end use of biomaterials. SOLO 3
- L03 Predict (5) the material selection and structure- function relations. SOLO 5
- L05 to define (3) traditional and novel technologies on drug delivery systems SOLO 3
Program Outcomes
- P01 PO1: To identify and use theoretical and applied knowledge as well as up-to-date/cutting edge laboratory techniques and analyses methods in the field of molecular biology and genetics.
- P02 PO2: To identify problems related to molecular biology and genetics.
- P03 PO3: To design and conduct experiments through hypothesis driven scientific research; and to analyze and interpret data to find solutions to molecular biology and genetics related problems.
- P04 PO4: To work independently and as part of research group in a multidisciplinary team setting
- P05 PO5: To apply the principles of scientific research ethics and academic integrity
- P06 PO6: To interpret, explain and present primary scientific literature and novel findings in oral, written and visual presentation formats
- P07 PO7: To evaluate experimental data and theoretical findings by using critical and analytical thinking techniques.
- P08 PO8: To use the currently acceptable process of preparing research proposals and manuscripts for publishing in scientific journals.
- P09 PO9: To apply the principles of molecular biology and genetics in generating/finding solutions to social problems / issues.
- P10 PO10: To identify and implement environmental and laboratory safety procedures.
- P11 PO11: To identify and apply the necessary professional skill set in projects and jobs involving independent and competitive careers in academia, industrial, medical or clinical research, science education, scientific writing and communication, health care, health care policy and civil service.
Po-Lo Matrix
| LO | P01 | P02 | P03 | P04 | P05 | P06 | P07 | P08 | P09 | P10 | P11 | Average |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L01 | - | - | - | - | - | - | - | - | - | - | - | - |
| L02 | - | - | - | - | - | - | - | - | - | - | - | - |
| L03 | - | - | - | - | - | - | - | - | - | - | - | - |
| L05 | - | - | - | - | - | - | - | - | - | - | - | - |