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TR

CURRENT TOPICS IN TUMOR BIOLOGY

Course
MDCN008 - CURRENT TOPICS IN TUMOR BIOLOGY
Department
Faculty of Medicine
Course Type
Course
Status
Required
Language
English
Credit
0
ECTS
2
T+P+L
2 + 0 + 0
Course Coordinator(s)
-
Prerequisite
-
Keywords

Course Description

This course covers current concepts and information about cancer. Students are informed about the genetic and molecular changes that occur during the transformation of normal cells into malignant cancer cells, the cellular and molecular mechanisms underlying cancer development and informs about current treatment approaches. Students acquire knowledge about tumor formation and techniques commonly used in cancer biology, develop their critical thinking skills and gain the ability to explain the cellular and molecular basis of disease. Students will gain the ability to explain possible types of gene mutations and how these mutations may contribute to cancer formation, describe the function of an oncogene and tumor suppressor genes, learn how cancer cells survive cell death, and explain current approaches in cancer treatment.

CURRENT TOPICS IN TUMOR BIOLOGY

Evaluation Tools (Active Term)

No evaluation items have been defined.

Course outcomes

No course outcomes have been defined yet.

Course Syllabus

Week Topic
Week 1 Introduction to Cancer and Historical Perspective
Week 2 Normal Cell Growth and Cell Cycle Control
Week 3 Oncogenes and Tumor Suppressor Genes
Week 4 DNA Damage, Repair Mechanisms, and Genomic Instability
Week 5 Apoptosis, Senescence, and Escape Mechanisms in Cancer
Week 6 Hallmarks of Cancer
Week 7 Tumor Microenvironment and Immune System
Week 8 Midterm Exam
Week 9 Angiogenesis and Tumor Nutrition
Week 10 Metastasis: Invasion and Cell Migration
Week 11 Cancer Stem Cells
Week 12 Epigenetic Changes in Cancer
Week 13 Cancer Treatment Approaches (Chemotherapy, Radiotherapy, Targeted Therapies, Immunotherapy)
Week 14 Current Cancer Research and Clinical Applications
Week 15 Final

Reference Books & Course Materials

  1. 01 Mendelsohn, The Molecular Basis of Cancer
  2. 02 Weinberg, The Biology of Cancer
  3. 03 Güncel derleme makaleleri, Current literature

Learning Outcomes

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Program Outcomes

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