BIOMATERIALS AND DRUG DELIVERY

Course Description

The objective is to develop a fundamental understanding of the definitions, classifications, properties and benefits of biomaterials. This course focuses on the fundamental understanding of implantable materials with respect to their design, analysis and use in human health. This course also includes evaluation of biomedical use, applications and biocompatibilities of biomaterials and provides the basic understanding of the controlled drug delivery systems and introduction to drug targeting. The course also includes the fundamentals of materials synthesis/fabrication, methods of characterisation/analysis, interactions between materials with tissues, quantitative analysis of material properties and how materials are used to impact human health. Also, It covers the application of engineering principles for designing and understanding the delivery of therapeutics.

BIOMATERIALS AND DRUG DELIVERY

Evaluation Tools (Active Term)

Course outcomes

1. 01 To classify (3) the classes of biomaterials used in biomedical applications, and explain (4) the various factors (materials properties, biologic response, etc.) that define the utility and applications of these materials.
2. 02 to Clarify (3) the knowledge of science and engineering to topics such as processing, characterization, and end use of biomaterials.
3. 03 Predict (5) the material selection and structure- function relations
4. 04 Constructing (4) ethical responsibility related to develop and use of biomaterials in clinical applications.
5. 05 -to define (3) traditional and novel technologies on drug delivery systems.
6. 06 Design (5) a project on a current biomaterial application, comparing the currently used materials, national and global industrial analysis and preparation of prersentation with applications

Course Syllabus

Reference Books & Course Materials

1. 01 Biomaterials - Temenoff and Mikos (Pearson Prentice Hall; ISBN 0-13-009710-1)
2. 02 Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids, Ram I. Mahato, CRC Press, ISBN 9780849323348
3. 03 Lecture Notes

Learning Outcomes

1. L01 To classify (3) the classes of biomaterials used in biomedical applications, and explain (4) the various factors (materials properties, biologic response, etc.) that define the utility and applications of these materials. SOLO 3.5
2. L02 to Clarify (3) the knowledge of science and engineering to topics such as processing, characterization, and end use of biomaterials. SOLO 3
3. L03 Predict (5) the material selection and structure- function relations. SOLO 5
4. L05 to define (3) traditional and novel technologies on drug delivery systems SOLO 3

Program Outcomes

1. Adequate knowledge in mathematics, science and engineering subjects pertaining to the relevant discipline; ability to use theoretical and applied knowledgein these areas in complex engineering problems
2. Ability to identify, formulate, and solve complex environmental problems; ability to select and apply proper analysis and modeling methods for this purpose.
3. Ability to design and conduct experiments, gather data, analyze and interpret results for investigating environmental problems or discipline specific research questions.
4. Ability to work efficiently in intra-disciplinary and multi-disciplinary teams; ability to work individually.
5. Ability to communicate effectively in English, both orally and in writing; knowledge of a minimum of one foreign language
6. Recognition of the need for lifelong learning; ability to access information, to follow developments in science and technology, and to continue to educate him/herself.
7. Consciousness to behave according to ethical principles and professional and ethical responsibility; knowledge on standards used in engineering practice.
8. Knowledge about business life practices such as project management, risk management, and change management; awareness in entrepreneurship, innovation; knowledge about sustainable development.
9. Knowledge about the global and social effects of engineering practices on health, environment, and safety, and contemporary issues of the century reflected into the field of engineering; awareness of the legal consequences of engineering solutions.

Po-Lo Matrix