TISSUE ENGINEERING

Course Description

The objective is to develop an overview of cell biology fundamentals, an extensive review on extracellular matrix and basics of receptors, followed by topics on cell-cell and cell-matrix interactions at both the theoretical and experimental levels. Subsequent lectures will cover the effects of physical (shear, stress, strain) and chemical (cytokins, growth factors) stimuli on cell function, emphasizing topics signal transduction processes. Tissue engineering will be introduced by reviewing tissue structure and function and the clinical need for tissue repair. An overview of scaffold design and processing for tissue engineering will be reviewed and the application of tissue engineering to specialized tissues and organs will then be addressed in depth.

TISSUE ENGINEERING

Evaluation Tools (Active Term)

No evaluation items have been defined.

Course outcomes

1. 01 describe basic principles behind human cell and tissue biology and cell
2. 02 describe the general types of biomaterials used in tissue engineering
3. 03 describe techniques utilized to design, fabricate, and functionally assess tissue engineering systems
4. 04 Explain basic principles of host response and tissue integration
5. 05 apply the combined knowledge of tissue organization and tissue engineering strategies to design a unique, reasonable tissue engineering solution
6. 06 appreciate ethical considerations for tissue engineering.
7. 07 Describe specific applications of TE constructs

Course Syllabus

Reference Books & Course Materials

1. 01 Principles of Tissue Engineering Ed. (Lanza, Langer, Vacanti)
2. 02 Tissue Engineering, Clemens Van Blitterswijk, Elsevier, Inc., First Edition. (2008) ISBN: 978-0-12-370869-4
3. 03 PowerPoint slides covering materials from other textbook and journal articles (60-70%)

Learning Outcomes

1. L01 Define and describe the application of tissue engineering. SOLO 2.5
2. L02 List the different methods used in the applications of tissue engineering SOLO 3
3. L03 List the different methods used in the applications of tissue engineering SOLO 3.3
4. L04 Explain basic principles of host response and tissue integration

Program Outcomes

1. P01 Should have sufficient knowledge in mathematics, science, and subjects specific to the relevant engineering discipline.
2. P02 Should have the ability to use theoretical and applied knowledge in mathematics, science, and related engineering disciplines in complex engineering problems.
3. P03 Should have the ability to detect, define, formulate, and solve complex engineering problems.
4. P04 Should have the ability to select and apply appropriate analysis and modeling methods to solve complex engineering problems.
5. P05 Should have the ability to design a complex system, process, device, or product to meet specific requirements under realistic constraints and conditions.
6. P06 Should have the ability to apply modern design methods.
7. P07 Should have the ability to develop, select, and use modern techniques and tools necessary for the analysis and solution of complex problems encountered in engineering applications.
8. P08 Should have the ability to use information technologies effectively.
9. P09 Should have the ability to design experiments, for the study of complex problems or discipline-specific research topics.
10. P10 Should have the ability to conduct experiments, collect data, analyze and interpret results for the study of complex problems or discipline-specific research topics.
11. P11 Should have the ability to work in intradisciplinary teams.
12. P12 Should have the ability to work in interdisciplinary teams.
13. P13 Should have the skills to work individually.
14. P14 Should have the ability to communicate effectively verbally and in writing.
15. P15 Should have the knowledge of at least one foreign language.
16. P16 Should be able to write effective reports, understand written reports, and prepare design and production reports.
17. P17 Should have the ability to make effective presentations.
18. P18 Should have the ability to give and have clear and understandable instructions.
19. P19 Should gain consciousness (awareness) about the necessity of lifelong learning.
20. P20 Should have the ability to access information.
21. P21 Should have the ability to follow developments in science and technology and constantly renew himself/herself.
22. P22 Should gain the awareness of professional and ethical responsibility and should act in accordance with ethical principles.
23. P23 Should gain knowledge about the standards used in engineering applications.
24. P24 Should gain knowledge about project management, risk management, and change management practices in business life.
25. P25 Should gain awareness about entrepreneurship, and innovation.
26. P26 Should gain knowledge about development in sustainability.
27. P27 Should gain knowledge about the effects of engineering practices on health, environment, and security at universal and social dimensions and the problems of the age reflected in the field of engineering.
28. P28 Awareness should be gained about the legal consequences of engineering solutions.

Po-Lo Matrix