BIOMATERIALS AND DRUG DELIVERY

Course Description

The objective is to develop a fundamental understanding of the definitions, classifications, properties and benefits of biomaterials. This course focuses on the fundamental understanding of implantable materials with respect to their design, analysis and use in human health. This course also includes evaluation of biomedical use, applications and biocompatibilities of biomaterials and provides the basic understanding of the controlled drug delivery systems and introduction to drug targeting. The course also includes the fundamentals of materials synthesis/fabrication, methods of characterisation/analysis, interactions between materials with tissues, quantitative analysis of material properties and how materials are used to impact human health. Also, It covers the application of engineering principles for designing and understanding the delivery of therapeutics.

BIOMATERIALS AND DRUG DELIVERY

Evaluation Tools (Active Term)

Course outcomes

1. 01 To classify (3) the classes of biomaterials used in biomedical applications, and explain (4) the various factors (materials properties, biologic response, etc.) that define the utility and applications of these materials.
2. 02 to Clarify (3) the knowledge of science and engineering to topics such as processing, characterization, and end use of biomaterials.
3. 03 Predict (5) the material selection and structure- function relations
4. 04 Constructing (4) ethical responsibility related to develop and use of biomaterials in clinical applications.
5. 05 -to define (3) traditional and novel technologies on drug delivery systems.
6. 06 Design (5) a project on a current biomaterial application, comparing the currently used materials, national and global industrial analysis and preparation of prersentation with applications

Course Syllabus

Reference Books & Course Materials

1. 01 Biomaterials - Temenoff and Mikos (Pearson Prentice Hall; ISBN 0-13-009710-1)
2. 02 Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids, Ram I. Mahato, CRC Press, ISBN 9780849323348
3. 03 Lecture Notes

Learning Outcomes

1. L01 To classify (3) the classes of biomaterials used in biomedical applications, and explain (4) the various factors (materials properties, biologic response, etc.) that define the utility and applications of these materials. SOLO 3.5
2. L02 to Clarify (3) the knowledge of science and engineering to topics such as processing, characterization, and end use of biomaterials. SOLO 3
3. L03 Predict (5) the material selection and structure- function relations. SOLO 5
4. L05 to define (3) traditional and novel technologies on drug delivery systems SOLO 3

Program Outcomes

1. P01 Should have sufficient knowledge in mathematics, science, and subjects specific to the relevant engineering discipline.
2. P02 Should have the ability to use theoretical and applied knowledge in mathematics, science, and related engineering disciplines in complex engineering problems.
3. P03 Should have the ability to detect, define, formulate, and solve complex engineering problems.
4. P04 Should have the ability to select and apply appropriate analysis and modeling methods to solve complex engineering problems.
5. P05 Should have the ability to design a complex system, process, device, or product to meet specific requirements under realistic constraints and conditions.
6. P06 Should have the ability to apply modern design methods.
7. P07 Should have the ability to develop, select, and use modern techniques and tools necessary for the analysis and solution of complex problems encountered in engineering applications.
8. P08 Should have the ability to use information technologies effectively.
9. P09 Should have the ability to design experiments, for the study of complex problems or discipline-specific research topics.
10. P10 Should have the ability to conduct experiments, collect data, analyze and interpret results for the study of complex problems or discipline-specific research topics.
11. P11 Should have the ability to work in intradisciplinary teams.
12. P12 Should have the ability to work in interdisciplinary teams.
13. P13 Should have the skills to work individually.
14. P14 Should have the ability to communicate effectively verbally and in writing.
15. P15 Should have the knowledge of at least one foreign language.
16. P16 Should be able to write effective reports, understand written reports, and prepare design and production reports.
17. P17 Should have the ability to make effective presentations.
18. P18 Should have the ability to give and have clear and understandable instructions.
19. P19 Should gain consciousness (awareness) about the necessity of lifelong learning.
20. P20 Should have the ability to access information.
21. P21 Should have the ability to follow developments in science and technology and constantly renew himself/herself.
22. P22 Should gain the awareness of professional and ethical responsibility and should act in accordance with ethical principles.
23. P23 Should gain knowledge about the standards used in engineering applications.
24. P24 Should gain knowledge about project management, risk management, and change management practices in business life.
25. P25 Should gain awareness about entrepreneurship, and innovation.
26. P26 Should gain knowledge about development in sustainability.
27. P27 Should gain knowledge about the effects of engineering practices on health, environment, and security at universal and social dimensions and the problems of the age reflected in the field of engineering.
28. P28 Awareness should be gained about the legal consequences of engineering solutions.

Po-Lo Matrix