ADVANCED PHARMACOGNOSY I
- Course
- PRCO503 - ADVANCED PHARMACOGNOSY I
- Department
- Pharmacognosy - English - Master
- Course Type
- Course
- Status
- Required
- Language
- English
- Credit
- 3
- ECTS
- 0
- T+P+L
- 2 + 0 + 2
- Course Coordinator(s)
- -
- Prerequisite
- -
- Keywords
Course Description
The plant and animal kingdom as source of drugs, General methods associated with the phytochemical investigation pf herbal products; Extraction of plant Material, separation and isolation of constituents: Sublimation, distillation, Fractional liberation, fractional chrystallization, Adsorbsion chromatography, Partition chromatagraphy, High performance liquid chromatography (HPLC), ThinLayer Chromatography(TLC), Gas-Liquid chromatography, Gel filtration chromatography, Electrochromatography, Basic metabolic pathways and the origin of secondary metabolites; Enzymes, Photosynthesis, Carbohydrate utilization, Glycosides, Fats and Fatty acids,, Aromatic biosynthesis, The shikimic acid pathway, The acetate hypothesis Amino acids biosynthesis, Peptides and proteins, Isoprenoid compounds The mevalonic acid pathway, Secondary metabolites, Stress compounds, Discovering new lead compounds in pharmaceutical research and development. Phytochemical variation within a species.
ADVANCED PHARMACOGNOSY I
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Course outcomes
- 01 Evaluate plant kingdom as source of drug
- 02 Analyze chemical constituent of plant drugs
- 03 Interprete basic metabolic pathways of secondary and primary metabolites
- 04 Evaluate the importance of carbohydrate containing plant drıgs
- 05 Evaluate the importance of glycoside containing plant drugs
- 06 Critisize between the relations of uses of plant drug with their chemical constituents
Course Syllabus
| Week | Topic |
|---|---|
| Week 1 | General methods associated with phytochemical investigation of herbal products, extraction of plant material |
| Week 2 | Extraction of plant material, separation and isolation of constituents |
| Week 3 | Chromatographic methods, adsorbsion, partision and thin layer chromatography, hihg performance liquid chromatography |
| Week 4 | Basic metabolic pathways and the origin of secondary metabolites, Enzymes |
| Week 5 | Carbohydrate utilization, carbohydrate containing drugs |
| Week 6 | Secondary metabolites, simple phenols and tannins |
| Week 7 | Antraquinones, identification and quantitation |
| Week 8 | Antraquinone containing drugs |
| Week 9 | Flavonoids identification and quantitation |
| Week 10 | Flavonoid containing drugs |
| Week 11 | Saponins; Steroidal saponins |
| Week 12 | Saponins: Triterpenoid saponins |
| Week 13 | Cardiac glycosides |
| Week 14 | Glucosinolates |
| Week 15 | - |
Reference Books & Course Materials
- 01 Fundamentals of Pharmacognosy and Phytotherapy(2013) Micheal Heinrich, Joanne Barnes, Simon Gibbons and Elizabeth Williamson, Churchill Livingstone, Elsevier
- 02 Trease and Evans Pharmacognosy (2009) William C. Evans, 16th ed. Saunders Elsevier, Edinburgh, London, New York , Philadelphia
- 03 Powdered Vegatable Drugs (1968) Betty Jacksoni Derek W. Snowden J. & A. Churchill Ltd. London
Learning Outcomes
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Program Outcomes
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