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TR

PHARMACEUTICAL TOXICOLOGY I

Course
PHAR308 - PHARMACEUTICAL TOXICOLOGY I
Department
Bioengineering - English - Master
Course Type
Scientific Preparation
Status
Required
Language
English
Credit
0
ECTS
0
T+P+L
0 + 0 + 0
Course Coordinator(s)
Prof. Dr. Mümtaz İŞCAN
Prerequisite
-
Keywords
-

Course Description

-

PHARMACEUTICAL TOXICOLOGY I

Evaluation Tools (Active Term)

Item Type Weight (%)
Mıdterm Midterm 40
Final Final 60
Total 100

Course outcomes

  1. 01 Students learned about the mechanism toxicity and ADME of major toxic substances
  2. 02 Students learned about the antidotes and how they can be applied in cases of poisonings
  3. 03 Students gained an understanding of the environmental issues related to industrial and commercial pollution
  4. 04 Students learned about the dangerous and adverse effects of materials that are used daily

Course Syllabus

Week Topic
Week 1 Introduction to Toxicology- History of Toxicology
Week 2 General Principles of Toxicology
Week 3 Disposition of Xenobiotics- Absorption, distribution and elimination
Week 4 Biotransformation of Xenobiotics I
Week 5 Biotransformation of Xenobiotics II
Week 6 Mechanisms of Toxicity
Week 7 Mechanisms of Toxicity and selective toxicity
Week 8 Midterm exam
Week 9 Mutagenesis and mutagenic agents
Week 10 Carcinogenesis and carcinogenic agents
Week 11 Teratogenesis and teratogenic agents
Week 12 Acute poisonings- Principles of general management I
Week 13 Acute poisonings- Principles of general management II
Week 14 Toxicity Tests
Week 15 Final exam

Reference Books & Course Materials

  1. 01 Pharmaceutical Toxicology (ULLA Postgraduate Pharmacy) (2006) By Gerard J. Mulder Ed.
  2. 02 Casarett & Doull's Essentials of Toxicology (Lange) – 3rd Ed. (2015) By Curtis D. Klaassen and John B. Watkins
  3. 03 Poison and Drug Overdose - 6th edition By Kent R. Olson
  4. 04 Boelsterli UA. Mechanistic Toxicology. CRC Press, Taylor and Francis Group, London, 2007

Learning Outcomes

  1. L01 Students learned about the mechanism toxicity and ADME of major toxic substances
  2. L02 Students learned about the antidotes and how they can be applied in cases of poisonings
  3. L03 Students gained an understanding of the environmental issues related to industrial and commercial pollution
  4. L04 Students learned about the dangerous and adverse effects of materials that are used daily

Program Outcomes

No program outcomes have been defined.

Po-Lo Matrix

The PO-LO matrix has not been populated yet.