CANCER BIOLOGY
- Course
- BIOT520 - CANCER BIOLOGY
- Department
- Biotechnology - English - Master
- Course Type
- Course
- Status
- Required
- Language
- English
- Credit
- 3
- ECTS
- 8
- T+P+L
- 3 + 0 + 0
- Course Coordinator(s)
- -
- Prerequisite
- -
- Keywords
Course Description
This course will cover the underlying molecular and cellular biology involved in carcinogenesis, tumor growth, and metastasis. The latest concepts in cancer biology and cancer therapeutics and a general appreciation of the rapid advances made in this area of biomedicine will be discussed. Certain topics such as cellular processes in cancer initiation and progression, modelling of different types of cancers in the laboratory, the genetic landscape of human cancers and novel therapeutics which target individual tumors based upon genetic signature will also be discussed. Additionally, this course aims to arm beginning graduate students with a working understanding of different cutting-edge methods that are being used to answer key questions in cancer biology and therapeutics.
CANCER BIOLOGY
Evaluation Tools (Active Term)
No evaluation items have been defined.
Course outcomes
No course outcomes have been defined yet.
Course Syllabus
| Week | Topic |
|---|---|
| Week 1 | Introduction to Cancer Biology and Genetics |
| Week 2 | Development and Progression of Cancer |
| Week 3 | Cell Cycle Regulation in Cancer |
| Week 4 | Proto-oncogenes and Oncogenes |
| Week 5 | Tumor Suppressor Genes |
| Week 6 | DNA Repair and Genome Stability |
| Week 7 | Hereditary Cancer Syndromes |
| Week 8 | Gene Regulation and Epigenetics in Cancer |
| Week 9 | Protein Regulation and Cellular Signaling |
| Week 10 | Telomeres, Telomerase and Cellular Immortality |
| Week 11 | Viral Carcinogenesis |
| Week 12 | Cancer Diagnosis and Conventional Therapies |
| Week 13 | Targeted Therapy and Immunotherapy |
| Week 14 | - |
| Week 15 | - |
Reference Books & Course Materials
- 01 Saria, M. G. (2018). Overview of cancer. In J. L. Watson (Ed.), Your guide to cancer prevention (pp. 1–11). Oncology Nursing Society
Learning Outcomes
- L01 Describe the molecular and cellular mechanisms underlying cancer initiation, progression, invasion, and metastasis. SOLO 3
- L02 Explain the roles of oncogenes, tumor suppressor genes, DNA repair pathways, and epigenetic alterations in cancer development. SOLO 4
- L03 Apply molecular and cellular biology principles to interpret the genetic basis of hereditary and sporadic cancers. SOLO 3
- L04 Analyze the mechanisms of viral carcinogenesis, genomic instability, and dysregulated signaling pathways involved in tumorigenesis. SOLO 4
- L05 Evaluate current diagnostic approaches and therapeutic strategies by integrating molecular, genetic, and clinical evidence. SOLO 5
Program Outcomes
No program outcomes have been defined.
Po-Lo Matrix
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