BIOSEPERATIONS
- Course
- BIOE506 - BIOSEPERATIONS
- Department
- Bioengineering - English - Master
- Course Type
- Course
- Status
- Required
- Language
- English
- Credit
- 3
- ECTS
- 0
- T+P+L
- 3 + 0 + 0
- Course Coordinator(s)
- -
- Prerequisite
- -
- Keywords
Course Description
In this course the separation of proteins, nucleic acids, and oligonucleotides from biological matrices is covered from analytical to process scales. Also in this course, the separation of monoclonal antibodies, which have found numerous uses as therapeutic and diagnostic agents will be covered. Analytical techniques include an interesting montage of chromatographic methods, capillary electrophoresis, isoelectric focusing, and mass spectrometry. Among separation and purification methods, liquid-liquid distribution, displacement chromatography, expanded bed adsorption, membrane chromatography, and simulated moving bed chromatography will be covered at length. Regulatory and economic considerations will be addressed, as are plant and process equipment and engineering process control. Application of DNA chip arrays, proteomics as well as evolving methodologies for a large number of drugs that are under development for treatment of cancer, AIDS, rheumatoid arthritis, and Alzheimer's disease will be discussed.
BIOSEPERATIONS
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