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TR

BIOMATERIALS AND DRUG DELIVERY

Course
BIOE225 - BIOMATERIALS AND DRUG DELIVERY
Department
Bioengineering - English - Undergraduate
Course Type
Course
Status
Required
Language
English
Credit
3
ECTS
7
T+P+L
3 + 0 + 0
Course Coordinator(s)
Asst. Prof. Dr. Nihal BAYIR
Prerequisite
Keywords

Course Description

The objective is to develop a fundamental understanding of the definitions, classifications, properties and benefits of biomaterials. This course focuses on the fundamental understanding of implantable materials with respect to their design, analysis and use in human health. This course also includes evaluation of biomedical use, applications and biocompatibilities of biomaterials and provides the basic understanding of the controlled drug delivery systems and introduction to drug targeting. The course also includes the fundamentals of materials synthesis/fabrication, methods of characterisation/analysis, interactions between materials with tissues, quantitative analysis of material properties and how materials are used to impact human health. Also, It covers the application of engineering principles for designing and understanding the delivery of therapeutics.

BIOMATERIALS AND DRUG DELIVERY

Evaluation Tools (Active Term)

Item Type Weight (%)
Midterm Exam Midterm 50
Final Exam Final 50
Total 100

Course outcomes

  1. 01 To classify (3) the classes of biomaterials used in biomedical applications, and explain (4) the various factors (materials properties, biologic response, etc.) that define the utility and applications of these materials.
  2. 02 to Clarify (3) the knowledge of science and engineering to topics such as processing, characterization, and end use of biomaterials.
  3. 03 Predict (5) the material selection and structure- function relations
  4. 04 Constructing (4) ethical responsibility related to develop and use of biomaterials in clinical applications.
  5. 05 -to define (3) traditional and novel technologies on drug delivery systems.
  6. 06 Design (5) a project on a current biomaterial application, comparing the currently used materials, national and global industrial analysis and preparation of prersentation with applications

Course Syllabus

Week Topic
Week 1 General Introduction to Biomaterial and Drug Delivery
Week 2 Introduction to Biomaterials (Definition, Classification)
Week 3 Mechanical and Physical properties of Materials
Week 4 Biometals
Week 5 Bioceramics
Week 6 Biocomposites
Week 7 Biopolymers
Week 8 Midterm Exam
Week 9 Drug Delivery Systems
Week 10 Controlled Drug delivery systems
Week 11 Release Kinetics
Week 12 Kinetic models
Week 13 Biomaterials for drug delivery
Week 14 Revision
Week 15 Final Exams

Reference Books & Course Materials

  1. 01 Biomaterials - Temenoff and Mikos (Pearson Prentice Hall; ISBN 0-13-009710-1)
  2. 02 Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids, Ram I. Mahato, CRC Press, ISBN 9780849323348
  3. 03 Lecture Notes

Learning Outcomes

  1. L01 To classify (3) the classes of biomaterials used in biomedical applications, and explain (4) the various factors (materials properties, biologic response, etc.) that define the utility and applications of these materials. SOLO 3.5
  2. L02 to Clarify (3) the knowledge of science and engineering to topics such as processing, characterization, and end use of biomaterials. SOLO 3
  3. L03 Predict (5) the material selection and structure- function relations. SOLO 5
  4. L05 to define (3) traditional and novel technologies on drug delivery systems SOLO 3

Program Outcomes

No program outcomes have been defined.

Po-Lo Matrix

The PO-LO matrix has not been populated yet.